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CLINICAL CHARACTERISTICS, PARACLINICAL FINDINGS, AND SURGICAL OUTCOMES OF COLORECTAL CANCER IN PROVINCIAL HOSPITALS OF THE MEKONG DELTA
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Abstract
Objective: To describe the clinical and paraclinical features and evaluate surgical treatment outcomes of CRC at provincial hospitals in the Mekong Delta region. Methods: We conducted a retrospective cross-sectional study of patients with confirmed CRC who underwent surgery at several provincial general hospitals in the Mekong Delta from January 2020 to August 2024. Data on clinical presentation (age, sex, symptoms, history), paraclinical findings (tumor location, histopathology, stage, laboratory results), and surgical outcomes (surgical approach, postoperative complications, mortality) were collected and analyzed descriptively. Results: A total of 250 patients were included, with mean age ~58 years. Males accounted for ~60%. Most patients (~70%) were from rural areas. The majority presented with gastrointestinal symptoms; abdominal pain (≈70%) and altered bowel habits (60%) were the most common, followed by rectal bleeding (55%). Tumors were most frequently located in the rectum (~40%) and sigmoid/descending colon (30%). All cases were adenocarcinoma, of which 80% were moderately differentiated. About 40% were diagnosed at stage III and 20% at stage IV. Laparoscopic surgery was performed in ~60% of cases (conversion to open in ~5%), and open surgery in 40%. Sphincter-preserving resection was achieved in ~70% of rectal cancer cases. The 30-day postoperative complication rate was 18%, including anastomotic leakage (~5%). The 30-day postoperative mortality was 1.2%. Conclusions: CRC patients in Mekong Delta provincial hospitals often presented with typical symptoms but a high proportion of advanced-stage disease. Surgical treatment yielded acceptable short-term outcomes, with laparoscopic resection proving safe and beneficial. Enhancing early detection and improving postoperative care (nutrition and follow-up) are recommended to further improve patient prognosis.
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Keywords
Colorectal cancer; clinical characteristics; paraclinical features; surgery; Mekong Delta.
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