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Date Published: 16/03/2026
Abstract Views: 68
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DOI: https://doi.org/10.51298/vmj.v560i1.17742
Issue
Vol. 560 No. 1 (2026)
Section
Các bài báo
How to Cite
Lê, K. T., & Trương, D. N. A. (2026). FACTORS ASSOCIATED WITH IMPROVED LEFT VENTRICULAR EJECTION FRACTION IN PATIENTS WITH CHRONIC HEART FAILURE UNDER OPTIMAL MEDICAL THERAPY. Vietnam Medical Journal, 560(1). https://doi.org/10.51298/vmj.v560i1.17742

FACTORS ASSOCIATED WITH IMPROVED LEFT VENTRICULAR EJECTION FRACTION IN PATIENTS WITH CHRONIC HEART FAILURE UNDER OPTIMAL MEDICAL THERAPY

Kim Tuyến Lê, Duy Ngọc Anh Trương

Main Article Content

Abstract

Objective: To investigate clinical, paraclinical, and treatment factors associated with the improvement of left ventricular ejection fraction (LVEF) in patients with chronic heart failure after 1 year. Methods: A retrospective cohort study on 160 patients with LVEF < at Tam Duc Heart Hospital. Patients were divided into Improved (LVEF increase > 10% and final > 40%) and Non-improved groups. Results: 44/160 (27.5%) patients showed improvement. The Improved group was significantly younger than the Non-improved group (55.3 + 9.6 vs. 61.4 + 15.9 years; p=0.018). Patients <60 years old had the highest improvement rate. Mineralocorticoid Receptor Antagonist (MRA) usage showed a statistically significant difference (p=0.042). The Improved group showed significant reduction in LV mass index (p<0.001). No significant association was found for gender, BMI, etiology, or comorbidities. Conclusion: Younger age is a significant predictor of LVEF improvement. Early identification of these factors aids in personalized management.

Article Details

Keywords

Predictors, improved ejection fraction, HFimpEF, age, MRA.

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