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CHARACTERIZATION OF THE N2 AUDITORY EVOKED POTENTIAL COMPONENT IN HEALTHY VIETNAMESE INDIVIDUALS AGED 18-21
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Abstract
Objective: This study aims to characterize the N2 component by establishing normative data for assessing auditory neural transmission in healthy. The study also evaluated relative factors, including hemispheric differences, gender, and correlations with P300. Methods: A cross-sectional descriptive study was conducted on 44 healthy adults (29 males, 15 females) aged 18-21. The “oddball paradigm” with auditory stimuli was employed to record N2 characteristics. Results: The N2 component appeared as a negative peak near 260 ms poststimulus. Amplitude decreased significantly across Cz-A12, C3-A12, and C4-A12 electrodes, with no significant latency differences. Gender showed no significant effect on amplitude or latency. A strong positive correlation between N2 and P300 amplitudes was observed across all electrodes. Conclusion: This study characterized the morphology, latency, and amplitude of the N2 component and analyzed its associations with relative factors. The data provide a reference for future neurophysiological research and clinical applications in Vietnam.
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Keywords
N2 component, auditory evoked potentials (AEPs), long-latency auditory evoked potentials (LLAEPs), oddball paradigm.
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