KHẢO SÁT TÌNH TRẠNG DỰ TRỮ SẮT HUYẾT TƯƠNG Ở BỆNH NHÂN BỆNH THẬN MẠN GIAI ĐOẠN CUỐI TẠI BỆNH VIỆN QUÂN Y 103

Abstract

Objective: Survey of plasma iron reserves and the relationship with hemodialysis status in patients with end-stage chronic kidney disease (ESRD) at 103 Military Hospital. Methods: A cross-sectional descriptive study was conducted on 157 ESRD patients treated at Military Hospital 103 from January 2022 to December 2023. Serum iron, ferritin, transferrin saturation (TSAT), and iron storage status were measured and compared between hemodialysis and non-hemodialysis groups. Determination of plasma iron reserve status is based on two indices: plasma ferritin concentration and TSAT. Results: Iron deficiency was common, accounting for 61.2% of patients (39.5% absolute iron deficiency; 21.7% functional iron deficiency). The prevalence of absolute iron deficiency was significantly higher in the hemodialysis group than in the non-hemodialysis group (47.0% vs. 19.0%, p = 0.003; OR = 3.76; 95% CI: 1.60–8.83). Conversely, functional iron deficiency was less frequent among hemodialysis patients compared with non-hemodialysis patients (15.7% vs. 38.1%, OR = 0.30; 95% CI: 0.13–0.68; p = 0.004). When combining both types, the overall iron deficiency rate in the hemodialysis group was 2.52 times higher than that of the non-hemodialysis group (OR = 2.52; 95% CI: 1.22–5.21; p = 0.012). Conclusion: Iron deficiency is highly prevalent among patients with ESRD. Maintenance hemodialysis is strongly associated with reduced iron stores. Regular monitoring of ferritin and transferrin saturation (TSAT) is essential to optimize anemia management using erythropoietin and appropriate iron supplementation in ESRD patients.