RESPONDING OF PREOPERATIVE RADIATION CHEMOTHERAPY IN THE TREATMENT OF ESOPHAGEAL CANCER AT VIET DUC FRIENDSHIP HOSPITAL
Main Article Content
Abstract
Objectives: Description of some clinical and paraclinical characteristics of patients with lower third esophageal cancer at Viet Duc Friendship Hospital who underwent preoperative radiotherapy and evaluation of treatment outcomes in this patient group. Objective and methods: A retrospective descriptive study of 40 patients with lower third esophageal squamous cell carcinoma who received preoperative radiotherapy followed by thoracoabdominal esophagectomy. Results: The average age was 55.8; male ratio was 97.5%; main symptoms were dysphagia 90%, chest pain 40%; average tumor length 4.82±1.1 cm; preoperative disease stage IIb, III, IVa were 5%, 85%, 10% respectively; average post-radiotherapy recovery time to surgery was 40.2 ± 12.5 days; complete clinical response 57.5%; complete paraclinical response 32.5%; complete pathological response (ypT0N0M0) 37.5%. There was no correlation between response rate and age, tumor length, tumor stage with p>0.05; the duration of post-radiotherapy recovery and response rate showed statistically significant correlation with p<0.05.
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Keywords
Concomitant preoperative radiation therapy, esophageal cancer, pathologic complete response.
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