THE CUMULATIVE RATES OF STROKE RECURRENCE: ANALYSIS BY TIME AND ETIOLOGY ACCORDING TO THE TOAST CLASSIFICATION

Văn Tân Võ , Quốc Hòa Hoàng, Phi Phong Cao

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Abstract

Background: Acute ischemic stroke (ICH) has always been one of the leading causes of death and disability, especially in developing countries. Furthermore, the risk of recurrence after ischemic stroke is quite high, especially in the first year, and can be up to 15 times higher than in the general population. Meanwhile, recurrent stroke always has higher mortality, sequelae and treatment costs than first stroke, understanding the cumulative rate of recurrent ischemic stroke helps doctors Clinical practice of secondary prevention would be better. Objectives: 1. Determine the cumulative stroke recurrence rate at 30 days, 90 days and 1 year after acute ischemic stroke. 2. Analysis of stroke causes (TOAST) affecting stroke recurrence. Subjects and methods: Patients with ischemic stroke were treated at the Department of Neurology, Nhan Dan Gia Dinh 's Hospital from January 2016 to December 2019. Using the cross-sectional, prospective descriptive method. Results: From 2016 to 2019, 1200 patients who met the sampling criteria were included in the study. Median follow-up was 1 year. In which, men accounted for 56.3% and the mean age of the subjects was 64.7 ± 13.4 with the lowest age being 25 and the highest being 104 with 53.5% of the patients in the age group ≥ 65. time after 30 days of follow-up, this value was 2.3% and increased to 8.8% and 11.9% at 90 days and 180 days of follow-up. The patient had a stroke due to vascular disease. Minor bleeding or unknown cause mainly relapsed within 3 months of follow-up. The majority of patients in the large atherosclerotic stroke group had a stroke recurrence after 6 months of follow-up, in which 50% of cases occurred after 9 months of follow-up. Conclusion: The cumulative recurrence rate after ischemic stroke at 30 days, 90 days and 1 year is high with values ​​of 6%, 11.88% and 23.29%, respectively. There was a significant difference in cumulative recurrence rates between the etiological subgroups of ischemic stroke at the time of follow-up. In particular, when compared with the small vessel disease group, the cumulative stroke recurrence rate of the heart embolization group was the highest, followed by the large atherosclerosis group

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References

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