NGHIÊN CỨU HIỆU QUẢ DỰ PHÒNG VÀ ĐIỀU TRỊ BỆNH NHÂN LOÉT CÙNG CỤT SỚM TẠI KHOA ĐỘT QUỴ - BỆNH VIỆN QUÂN Y 103

Abstract

Objective: Evaluation of the Preventive and Therapeutic Effectiveness of Sanyrène Spray in Early-Stage Sacral Pressure Injuries and the Association Between Treatment Outcomes and Selected Clinical and Paraclinical Characteristics in Patients at the Stroke Department, 103 Military Hospital. Methods: A cross-sectional descriptive and interventional clinical study with a before-and-after comparison was conducted in stroke inpatients at the Stroke Department – 103 Military Hospital. Patients at high risk of developing pressure ulcers or presenting with early-stage pressure ulcers were treated with Sanyrene spray. The efficacy of ulcer healing was evaluated at 1, 2, 3, and 4 weeks of treatment, and the time to complete ulcer healing was assessed. Results: The mean age of the study population was 67.3 ± 16.1 years, with the majority of patients aged over 70 years (49.2%). There were no significant differences between the two groups regarding age and gender. Most participants were retired officers, accounting for more than 45%. The proportion of patients achieving wound healing within <5 days was 50% in the Sanyrene-treated group, compared to 36.7% in the control group. A statistically significant association was observed between the Glasgow Coma Scale (GCS) score and Body Mass Index (BMI) with the time to pressure ulcer healing (p < 0.05). Patients with lower GCS and BMI values exhibited a longer healing duration. Conclusion: The Sanyrène spray demonstrated significant efficacy in the treatment of early-stage sacral pressure ulcers, contributing to shorter wound-healing time, reduced ulcer progression, and improved skin condition in pressure-bearing areas. The proportion of patients achieving wound closure within 5 days reached 50% in the Sanyrène-treated group, compared to 36.7% in the control group. Patients with lower Glasgow Coma Scale (GCS) scores (5–8 points) or lower Body Mass Index (BMI < 18.5) experienced delayed wound healing, whereas those with normal BMI and better consciousness levels showed faster recovery.