PROGNOSTIC FACTORS ASSOCIATED WITH THE SUCCESS OF EXTRACORPOREAL CARBON DIOXIDE REMOVAL IN PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME
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Abstract
Objective: To identify prognostic factors associated with the success of extracorporeal carbon dioxide removal (ECCO₂R) in patients with acute respiratory distress syndrome (ARDS). Subjects: ARDS patients indicated for ECCO₂R the Center for Critical Care Medicine – Bach Mai Hospital from July 2024 to September 2025. Methods: A retrospective descriptive observational study with convenient sampling included all ARDS patients who underwent ECCO₂R during the study period; data were collected from medical records and case report forms and analyzed using SPSS. Results: A total of 15 patients with ARDS were enrolled in this study, the majority were male, with a mean age of 58,5 ± 15,1 years and a mean SOFA score of 9; 66,7% required norepinephrine support. Univariate logistic regression analysis revealed no factor reaching statistical significance; however, a favorable trend was observed in patients with a higher ventilatory ratio (VR, OR = 3,106; p = 0,145). Unfavorable factors included older age (OR = 0,24; p = 0,14), the presence of comorbidities (OR = 0,71; p = 0,55), and higher SOFA scores (OR = 0,65; p = 0,27). Conclusion: In patients with ARDS undergoing ECCO₂R, a higher VR was associated with a trend toward greater clinical success, whereas advanced age, comorbidities, and higher SOFA scores were unfavorable factors.
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Keywords
ECCO₂R; ARDS; hemodynamics; ventilatory ratio; prognostic factors
References
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