ĐẶC ĐIỂM RỐI LOẠN NHỊP TIM TRÊN HOLTER ĐIỆN TÂM ĐỒ 24 GIỜ Ở BỆNH NHÂN BỆNH CƠ TIM PHÌ ĐẠI

Abstract

Objectives: Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease characterized by myocardial hypertrophy, which may lead to varying degrees of left ventricular outflow tract obstruction. One of the most frequent and potentially life-threatening complications of HCM is cardiac arrhythmia. This study aimed to describe the characteristics of cardiac arrhythmias detected by 24-hour Holter electrocardiography and to investigate several factors associated with arrhythmias in patients with hypertrophic cardiomyopathy at the Vietnam National Heart Institute, Bach Mai Hospital. Methods: A cross-sectional case-series study was conducted from October 2023 to February 2025, including 39 patients diagnosed with hypertrophic cardiomyopathy at Bach Mai Hospital. Results: Among the 39 HCM patients enrolled in the study, the most common arrhythmia was premature ventricular contractions, observed in 61.5% (24/39) of patients. Atrial fibrillation was present in 38.46% (15/39), ventricular tachycardia in 17.95% (7/39), and atrial tachycardia in 5.13% (2/39) of patients. In HCM patients with atrial fibrillation, left atrial diameter, left ventricular end-diastolic diameter, and the proportion of patients with left ventricular ejection fraction <40% were significantly higher compared with those without atrial fibrillation (p < 0.05). The prevalence of systolic anterior motion (SAM) was significantly higher in patients with premature ventricular contractions than in those without premature ventricular contractions (p = 0.01). Conclusions: Cardiac arrhythmias are common in patients with hypertrophic cardiomyopathy, with premature ventricular contractions and atrial fibrillation being the two most frequently observed arrhythmias.