ĐẶC ĐIỂM NHIỄM KHUẨN ĐA KHÁNG KHÁNG SINH TRÊN BỆNH NHÂN BỎNG NẶNG

Abstract

Objectives: Evaluation of the characteristics of multidrug-resistant bacterial infections in severe burns patients. Methods: A total of 131 patients with severe burns were treated at the Intensive Care Unit of Le Huu Trac National Burn Hospital from January 2023 to December 2023, with 321 wound samples, 305 urine samples, and 118 blood samples collected. Results: Among the wound samples, 37.38% were positive for bacteria, predominantly Gram-negative bacteria (81.97%). The most commonly isolated organism was Pseudomonas aeruginosa (41.80%), followed by Acinetobacter baumannii (27.05%). The majority of the bacterial isolates were multidrug-resistant, with the highest rates observed in Acinetobacter baumannii (93.94%) and Enterobacteriaceae (91.67%). Out of the 118 blood samples, 43 (36.44%) were positive for bacteria, with the majority being Gram-negative bacteria (72.34%). The most frequently isolated organism was Pseudomonas aeruginosa (36.17%), followed by Acinetobacter baumannii (27.66%). All isolates of Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacteriaceae, and Staphylococcus spp. were identified as multidrug-resistant bacteria. Bacterial growth was detected in 6.89% of urine samples, of which multidrug-resistant bacteria accounted for the majority (80.95%). At all post-burn culture time points, Gram-negative bacteria predominated in wound, blood, and urine specimens. Conclusion: At all post-burn culture time points, Gram-negative bacteria predominated in wound, blood, and urine specimens. The majority of isolates were multidrug-resistant bacteria.