PRELIMINARY RESULTS OF CT-GUIDED SYMPATHETIC PLEXUS NEUROLYSIS FOR PAIN MANAGEMENT

Thị Kim Khuyên Mai, Gia Khánh Đinh , Minh Chi Phạm , Phú Quý Đinh , Bá Tú Trần, Thị Thuỳ Linh Trần

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Abstract

Objective: This study aimed to evaluate the analgesic efficacy of computed tomography (CT)-guided sympathetic plexus neurolysis in patients with malignancies involving the supramesocolic abdominal organs and pelvic viscera. Materials and Methods: A combined prospective and retrospective descriptive study was conducted on 47 patients (45 undergoing celiac plexus neurolysis and 2 undergoing superior hypogastric plexus neurolysis) at the 108 Military Central Hospital between June 2019 and December 2024. Pain intensity was assessed using the Visual Analog Scale (VAS) and BPI before and after the procedure, and all procedure-related adverse events were documented. Results: In the celiac plexus group, the mean pre-procedural VAS score was 7.0 ± 1.1. After two weeks, 37 of 45 patients (82.2%) achieved a ≥50% reduction in VAS score. The anterior approach was the most frequently used. The most common adverse event was transient diarrhea (37.8%), while one case of cerebral infarction was recorded. In the superior hypogastric plexus group, the mean baseline VAS score was 8.0 ± 0.8 and decreased by approximately 50% after the procedure. Both procedures were performed via the posterior approach; one patient experienced transient sciatic nerve injury that resolved within two month. Conclusion: CT-guided sympathetic plexus neurolysis using absolute alcohol is a safe and effective interventional technique for managing cancer-related pain in patients with advanced disease, providing significant pain relief with an acceptable complication rate.

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References

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