MINIMALLY INVASIVE MANAGEMENT OF DYSFUNCTIONAL HEMODIALYSIS ARTERIOVENOUS ACCESS: EFFECTIVENESS OF NON-SURGICALREVASCULARIZATION IN OLDER ADULTS AT THONG NHAT HOSPITAL

Duy Tân Nguyễn, Đỗ Nhân Nguyễn, Ngọc Hạnh Huỳnh

Main Article Content

Abstract

Background: Dysfunction of hemodialysis arteriovenous access (AVF) is a very common complication. Surgical treatment has long been proven effective and has been the preferred approach. However, management becomes particularly challenging in older patients with end-stage kidney disease, frailty, and multiple comorbidities. Minimally invasive strategies are therefore a top priority in this population. Accordingly, the effectiveness of non-surgical endovascular (EV) for dysfunctional AVF warrants evaluation. Object and Methods: This descriptive cross-sectional study included 49 patients aged ≥60 years with dysfunctional AVF who underwent EV at Thong Nhat Hospital between 01/2023-06/2025. Clinical characteristics, access-related lesions, technical outcomes, early hemodynamic improvement (access flow and continuous bruit), and in-hospital complications were evaluated. Results and discussion: A high burden of comorbidities was observed, including hypertension (83.7%) and diabetes mellitus (46.9%), malnutrition (BMI <18.5 kg/m²: 26.5%). Immature AVF dysfunction was commonly associated with anastomotic lesions and concomitant thrombosis, whereas mature AVF dysfunction was mainly related to outflow vein stenosis. EV achieved favorable and comparable technical success rates between the two groups (83.3% vs. 86.4%; p>0.05), with marked improvement in access flow and restoration of continuous bruit in more than 90% of cases. The rate of major complications was low, and no procedure-related in-hospital mortality was recorded. Conclusion: EV for dysfunctional AVF in older adults is a safe and effective approach, providing significant early hemodynamic improvement. Given its minimally invasive nature and vessel-preserving advantages, endovascular intervention should be considered a preferred treatment option for managing hemodialysis access dysfunction in the elderly population.

Article Details

References

1. Al-Jaishi AA, Liu AR, Lok CE, et al. Complications of the arteriovenous fistula: a systematic review. J Am Soc Nephrol. 2020;31(3):597–608.
2. Vascular Access Work Group. Clinical practice guidelines for vascular access. Am J Kidney Dis. 2019;73(4 Suppl 1):S1–S164.
3. Schmidli J, Widmer MK, Basile C, et al. Editor’s Choice – Vascular access: 2018 clinical practice guidelines of the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg. 2018;55(6):757–818.
4. Holden A, et al. IN.PACT AV Access Randomized Trial: 12-Month Clinical Outcomes. J Vasc Interv Radiol. 2022;33(8):884–894.e7.
5. Lok CE. Hemodialysis Vascular Access: Core Curriculum 2025. Am J Kidney Dis. 2025;85(1):e1-e18.
6. De Oliveira Harduin L, et al. Guidelines for Hemodialysis Vascular Access: Brazilian Society. J Vasc Bras. 2023;22:e20230052.
7. Lookstein RA, Glickman MH, Holden A, et al. Endovascular treatment standards for dialysis access dysfunction. J Vasc Interv Radiol. 2023;34(8):1259–1271.
8. Dias BF, et al. Hemodialysis vascular access in the elderly. Nefrologia. 2025;S0211-6995(24)00099-7.
9. McDonnell SM, et al. Frailty screening for determination of hemodialysis access surgical outcomes. J Vasc Surg. 2024;79(3).
10. Lookstein RA, et al. IN.PACT AV Access Randomized Trial of Drug-Coated Balloons for Dysfunctional Arteriovenous Fistulas: Clinical Outcomes Through 36 Months. J Vasc Interv Radiol. 2023;34(8):1272-1282.e2.
11. Anderson EM, et al. The Impact of Reintervention on Arteriovenous Fistula Maturation and Functional Patency in the Hemodialysis Fistula Maturation Stud. Kidney Med. 2025 26;7(8):101036.