Article Sidebar

PDF
Date Published: 13/01/2022
Abstract Views: 552
Views PDF: 209
DOI: https://doi.org/10.51298/vmj.v509i2.1798
Issue
Vol. 509 No. 2 (2021)
Section
Các bài báo
How to Cite
Việt Anh, V. ., Thanh Tùng, N. ., & Thị Bích Phượng, N. . (2022). THE INITIAL TREATMENT RESULTS OF TWO ESTHESIONEUROBLASTOMA CLINICAL CASES AT THE NATIONAL CANCER HOSPITAL. Vietnam Medical Journal, 509(2). https://doi.org/10.51298/vmj.v509i2.1798

THE INITIAL TREATMENT RESULTS OF TWO ESTHESIONEUROBLASTOMA CLINICAL CASES AT THE NATIONAL CANCER HOSPITAL

Vũ Việt Anh1,, Ngô Thanh Tùng1, Nguyễn Thị Bích Phượng1
1 K Hospital

Main Article Content

Abstract

Objectives: This study aimed at describing clinical, subclinical characteristics, and the initial result of treatment on two cases of olfactory neuroblastoma by surgical treatment combined with chemotherapy and radiotherapy at the National Cancer Hospital. Subjects and methods: The cross-sectional study and reporting a cluster of cases was conducted on two patients with a convenient sampling method. The period is from October 2020 to October 2021. Results: The sexes of the two patients were male, with ages 44 and 50 respectively. The main clinical symptoms of the patients were stuffy nose, one-sided nasal bleeding, migraine headache. The subclinical test results were consistent with the medical literature describing the disease. Applying surgical treatment method combining chemotherapy and radiation therapy at the same time after surgery, with a dose of 60Gy/30fx and chemical Cisplatin 100mg/m2 for a 3-week multi-cycle. Treatment results showed that two patients responded completely and had no complications on the hematopoietic system. Conclusion: The surgical treatment combined with chemotherapy and radiotherapy at the same time after surgery initially has a good effect on these patients.

Article Details

Keywords

Esthesioneuroblastoma, National Cancer Hospital

References

1. Olfactory neuroblastoma - PubMed. https://pubmed.ncbi.nlm.nih.gov/20596981/
2. Kuan EC, Nasser HB, Carey RM, et al. A Population-Based Analysis of Nodal Metastases in Esthesioneuroblastomas of the Sinonasal Tract. Laryngoscope. 2019;129(5):1025-1029.
3. Dulguerov P, Calcaterra T. Esthesioneuroblastoma: The UCLA experience 1970–1990. The Laryngoscope. 1992;102(8):843-849.
4. Kadish S, Goodman M, Wang CC. Olfactory neuroblastoma - A clinical analysis of 17 cases. Cancer. 1976;37(3):1571-1576.
5. Esthesioneuroblastoma: Results and Outcomes of a Single Institution’s Experience - PubMed. Accessed March 12, 2021. https://pubmed.ncbi.nlm.nih.gov/19721769/
6. Broich G, Pagliari A, Ottaviani F. Esthesioneuroblastoma: A general review of the cases published since the discovery of the tumour in 1924. 1924;17(2):683-706.
7. Dulguerov P, Allal AS, Calcaterra TC. Esthesioneuroblastoma: a meta-analysis and review. 2001;2(11):683-690.
8. El Kababri M, Habrand JL, Valteau-Couanet D, Gaspar N, Dufour C, Oberlin O. Esthesioneuroblastoma in Children and Adolescent: Experience on 11 Cases with Literature Review. Journal of Pediatric Hematology/Oncology. 2014;36(2):91-95.