TÌNH TRẠNG TUÂN THỦ ĐIỀU TRỊ VÀ CÁC YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN VIÊM MŨI XOANG MẠN TÍNH TẠI BỆNH VIỆN TAI MŨI HỌNG TP. HỒ CHÍ MINH

Abstract

Background: Chronic rhinosinusitis (CRS) is a common otolaryngologic disease that reduces quality of life and creates a socioeconomic burden. Long-term medication adherence tends to decline over time and is influenced by socioeconomic factors. Objective: To determine medication adherence rates at 3 and 6 months and to identify factors associated with adherence among patients with CRS at an ENT hospital in Ho Chi Minh City, Vietnam. Methods: A prospective longitudinal study was conducted on 72 adult CRS patients treated at the Rhinology Department; 68 completed the 6-month follow-up and were analyzed. Medication adherence was assessed using the 8-item Morisky Medication Adherence Scale (MMAS-8), dichotomized at a cut-off of 6 points. Independent variables included age, sex, educational level, distance to the hospital, economic status, family support, and treatment regimen. Results: At 3 months, 92.6% (63/68) of patients were adherent, decreasing to 63.2% (43/68) at 6 months (p < 0.05). No significant associations were observed between adherence and demographic or socioeconomic variables at 3 months. At 6 months, higher educational level, shorter distance to the hospital, and better economic status were significantly associated with good adherence, whereas age, sex, and family support were not. Conclusion: Medication adherence in CRS patients is initially high but declines significantly after 6 months. Long-term adherence is strongly influenced by educational level, distance to care, and economic status. Targeted interventions to improve health literacy, reduce access barriers, and support financially vulnerable patients are needed to maintain adherence.