MỐI LIÊN QUAN GIỮA NỒNG ĐỘ ALBUMIN, PROTEIN TOÀN PHẦN VÀ TỶ LỆ THIẾU MÁU Ở BỆNH NHÂN BỆNH THẬN MẠN LỌC MÁU CHU KỲ

Abstract

Objective: To evaluate the association between serum albumin and total protein levels with hemoglobin concentration and anemia status in patients with chronic kidney disease undergoing maintenance hemodialysis. Subjects and Methods: A cross-sectional study with multivariate linear regression analysis was conducted on 62 patients with end-stage renal disease undergoing maintenance hemodialysis at Thai Binh University of Medicine Hospital from October 2025 to January 2026. Results: The mean age of the patients was 54.82 ± 15.50 years; males accounted for 48.39%. The primary cause of kidney failure was chronic glomerulonephritis (74.19%). The mean serum albumin level was 37.02 ± 5.79 g/L; total protein was 67.53 ± 6.33 g/L; and hemoglobin was 103.38 ± 17.64 g/L. The prevalence of hypoalbuminemia was 29.03%, low total protein was 14.52%, and anemia accounted for 87.10%. Multivariable linear regression analysis showed that serum albumin levels and duration of dialysis were positively associated with hemoglobin concentration after adjusting for age and total protein. Conclusion: Serum albumin levels are associated with hemoglobin concentration in patients undergoing maintenance hemodialysis. Longitudinal studies are needed to determine a causal relationship.