ENDOSCOPIC FEATURES, HISTOPATHOLOGICAL CHARACTERISTICS, AND OUTCOMES OF ENDOSCOPIC POLYPECTOMY FOR NON-PEDUNCULATED COLORECTAL POLYPS ≥20 MM

Thanh Liêm Nguyễn, Thị Thúy Loan Lê

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Abstract

Background: Endoscopic polypectomy of large non-pedunculated polyps carries a high risk of bleeding. Objective: To describe the endoscopic features, histopathological characteristics, and Outcomes of endoscopic polypectomy of non-pedunculated colorectal polyps ≥20 mm. Materials and Methods: This descriptive cross-sectional study involved 31 patients with 35 non-pedunculated polyps ≥20 mm in the colon and rectum. All polyps were resected using either endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) techniques, combined with clip placement to close the resection site. The resected polyps were sent for histopathological examination. Results: The majority of patients (87.1%) had one polyp. Polyps were more commonly located in the colon than in the rectum. Neoplastic polyps accounted for the majority (77.1%), followed by non-neoplastic polyps (14.3%). Three polyps (8.6%) were cancerous. Twenty-six polyps (74.3%) were resected using the EMR technique, and 9 polyps (25.7%) using the ESD technique. The overall success rate of polyp resection was 97.1% (34/35). One polyp resected using ESD failed, representing 2.9%. All 34 successfully resected polyps were closed with clips, achieving a 100% success rate. There were no complications or adverse events in the 30 days following the procedure. Conclusion: Non-pedunculated colorectal polyps ≥20 mm have a high malignancy rate. The treatment of these polyps using EMR or ESD techniques combined with clip closure of the resection site is highly effective in preventing delayed complications.

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References

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