ĐẶC ĐIỂM HỘI CHỨNG GAN THẬN Ở BỆNH NHÂN XƠ GAN TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN

Abstract

Objective: To describe the characteristics of hepatorenal syndrome and analyze some related factors in cirrhotic patients at Thai Nguyen Central Hospital. Methods: A prospective descriptive study was conducted on 125 cirrhotic patients with hepatorenal syndrome treated from January to December 2025. Diagnosis and classification of hepatorenal syndrome were based on the criteria of the International Ascites Association. Clinical, laboratory, and outcome characteristics were collected and analyzed. Results: The majority of patients were male (96%), with an average age of 57.7 ± 11.4. Hepatorenal syndrome - acute renal injury (HRS-AKI) accounted for 89.6%, with stages 1A and 1B being the most common. Serum urea and creatinine levels increased progressively with disease severity, while eGFR decreased significantly (p < 0.05). Severe anemia (22.3%) was more common in HRS-AKI than in HRS-CKD (p < 0.05). The mortality rate in HRS-AKI patients (36.6%) was higher than in HRS-CKD patients (7.7%) (p < 0.05). Conclusion: Hepatorenal syndrome in cirrhotic patients mainly manifests in an acute form, progressing through stages with increased urea and creatinine and decreased glomerular filtration rate, often accompanied by anemia, and has a higher mortality prognosis compared to the chronic form.