NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ CĂN NGUYÊN GIẢM HAI HOẶC BA DÒNG TẾ BÀO MÁU NGOẠI VI TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y - DƯỢC HUẾ

Abstract

Objectives: To analyze the etiologies of bicytopenia and pancytopenia in patients presenting to and treated at Hue University of Medicine and Pharmacy Hospital. Methods: A cross-sectional descriptive study was conducted on 221 patients diagnosed with bicytopenia or pancytopenia. Clinical features, laboratory findings, and underlying etiologies were collected and analyzed. Results: Bicytopenia was more frequent than pancytopenia (70.58% vs 29.42%), with anemia combined with thrombocytopenia being the most common pattern (33.93%). Clinical and laboratory manifestations were diverse; severe neutropenia (<0.5 G/L) was observed in 4.52% of patients. The most common etiologies were adverse effects of cancer chemotherapy (24.89%) and liver cirrhosis (approximately 26%). Patients with unidentified causes accounted for 38.46% of cases. Conclusion: Bicytopenia is a common condition in general hospital settings, with etiologies mainly related to chronic liver disease and cancer chemotherapy. These findings provide an overview of real-world clinical, laboratory, and etiological characteristics, thereby supporting diagnostic orientation and patient management in clinical practice.