Article Sidebar

PDF
Date Published: 13/01/2022
Abstract Views: 185
Views PDF: 152
DOI: https://doi.org/10.51298/vmj.v509i2.1827
Issue
Vol. 509 No. 2 (2021)
Section
Các bài báo
How to Cite
Ngọc Trang, N. ., Nam Hương, K. ., & Thị Hồng Thi, P. . (2022). MORTALITY AND PROGNOSTIC FACTORS OF INFECTIVE ENDOCARDITIS. Vietnam Medical Journal, 509(2). https://doi.org/10.51298/vmj.v509i2.1827

MORTALITY AND PROGNOSTIC FACTORS OF INFECTIVE ENDOCARDITIS

Nguyễn Ngọc Trang1,, Khổng Nam Hương2, Phạm Thị Hồng Thi2
1 Vinh Phuc General Hospital
2 Vietnam National Heart Institute, Bach Mai Hospital

Main Article Content

Abstract

Objectives: To investigate the mortality rate and find out some factorsthe prognosis of mortality in patients with infective endocarditis. Subjects and methods: A retrospective, prospective descriptive study was conducted onpatients diagnosed with infective endocarditis according to improved DUKE criteria and treated at Bach Mai hospital from January 2019 to February 2021. Research target: all-cause mortality in hospital and in 6 months. Results: Mean age was 49.7 ± 19.3, male 64.5%. During treatment, surgery was performed in 42.9% of patients. The in-hospital mortality rate was 10.3% and the 6-month mortality rate was 25.4%. In multivariate analysis, the independent prognostic factors for death were white blood cell count (OR= 1.17; 95% CI 1.03 - 1.33), blood urea nitrogen level (OR=1.26; 95% CI 1.04 - 1.53). glomerular filtration rate (OR= 1.03; 95% CI 1 - 1.07) and surgical treatment (OR= 0.03; 95% CI 0.01-0.39).

Article Details

Keywords

infective endocarditis, mortality, prognostic factors

References

1. Habib G, Lancellotti P, Antunes MJ, et al. 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC)Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J. 2015;36(44):3075-3128. doi:10.1093/eurheartj/ehv319
2. Sci-Hub | Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications. Circulation, 132(15), 1435–1486 | 10.1161/ CIR.0000000000000296. Accessed October 24, 2021. https://sci-hub.se/ 10.1161/ CIR.0000000000000296
3. Wu Z, Chen Y, Xiao T, Niu T, Shi Q, Xiao Y. Epidemiology and risk factors of infective endocarditis in a tertiary hospital in China from 2007 to 2016. BMC Infect Dis. 2020;20(1):428. doi:10.1186/s12879-020-05153-w
4. Chu VH, Cabell CH, Benjamin DK, et al. Early predictors of in-hospital death in infective endocarditis. Circulation. 2004;109(14):1745-1749. doi:10.1161/01.CIR.0000124719.61827.7F
5. Li JS, Sexton DJ, Mick N, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis Off Publ Infect Dis Soc Am. 2000;30(4):633-638. doi:10.1086/313753
6. Nguyễn Thị Thu Hoài. Viêm nội tâm mạc nhiễm khuẩn tại Bệnh viện Bạch Mai, 2012 - 2017. 2019. Published online 2019.
7. Siciliano RF, Gualandro DM, Bittencourt MS, et al. Biomarkers for prediction of mortality in left-sided infective endocarditis. Int J Infect Dis IJID Off Publ Int Soc Infect Dis. 2020;96:25-30. doi:10.1016/j.ijid.2020.03.009
8. Ortega-Loubon C, Muñoz-Moreno MF, Andrés-García I, et al. Nosocomial Vs. Community-Acquired Infective Endocarditis in Spain: Location, Trends, Clinical Presentation, Etiology, and Survival in the 21st Century. J Clin Med. 2019; 8(10):E1755. doi:10.3390/jcm8101755
9. Wu Z, Chen Y, Xiao T, Niu T, Shi Q, Xiao Y. Epidemiology and risk factors of infective endocarditis in a tertiary hospital in China from 2007 to 2016. BMC Infect Dis. 2020;20(1):428. doi:10.1186/s12879-020-05153-w