ASSOCIATION BETWEEN CENTRAL OBESITY AND GLYCEMIC CONTROL AND SELECTED METABOLIC PARAMETERS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH A NON-OBESE BMI

Hoàng Trung Nguyễn, Đức Minh Tống

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Abstract

Objective: To evaluate the prevalence of central obesity and its association with metabolic control in patients with type 2 diabetes mellitus (T2DM) with non-obese BMI. Methods: A cross-sectional descriptive study was conducted on 85 T2DM patients with BMI 18.5-24.9 kg/m², managed at Military Hospital 103 from January 2024 to December 2025. Anthropometric, biochemical, and metabolic parameters were collected and analyzed. Results: The prevalence of central obesity was 62.4%. The central obesity group had significantly higher mean HbA1c (8.0 ± 1.3 vs. 7.2 ± 1.0%; p = 0.003), higher rates of suboptimal glycemic control (67.9% vs. 40.6%; p = 0.014), higher triglycerides, and lower HDL-C. Multivariable logistic regression identified central obesity as an independent predictor of poor glycemic control (adjusted OR = 2.84; 95%CI: 1.12-7.18; p = 0.028), alongside diabetes duration ≥5 years and insulin-based therapy. Conclusion: Central obesity is prevalent and independently associated with poor metabolic control in T2DM patients with non-obese BMI.

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References

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