FACTORS ASSOCIATED WITH 3-MONTH FUNCTIONAL OUTCOMES AFTER DECOMPRESSIVE HEMICRANIECTOMY FOR LARGE HEMISPHERIC INFARCTION WITH MALIGNANT EDEMA

Anh Đức Trần

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Abstract

Objective: To analyze factors associated with unfavorable functional outcomes at 3 months in patients with massive cerebral infarction accompanied by malignant cerebral edema who underwent decompressive hemicraniectomy. Methods: A descriptive study with analytic components was conducted on 52 patients who underwent decompressive hemicraniectomy for massive cerebral infarction with malignant cerebral edema at Military Hospital 103 from January 2022 to December 2025. Functional outcome was assessed using the modified Rankin Scale (mRS) at 3 months after surgery. Results: Factors associated with unfavorable outcomes included age ≥ 60 years (p = 0.003), preoperative GCS < 10 (p = 0.005), admission NIHSS ≥ 20 (p = 0.012), midline shift > 10 mm (p = 0.006), preoperative hemorrhagic transformation (p = 0.020), and time from symptom onset to surgery > 48 hours (p = 0.041). Preoperative recanalization was associated with better outcomes (p = 0.048). Conclusion: Older age, greater clinical and radiological severity, and delayed surgery were associated with unfavorable 3-month outcomes in patients with massive cerebral infarction accompanied by malignant cerebral edema.

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References

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