RESISTANCE PATTERNS OF PSEUDOMONAS AERUGINOSA ISOLATED AT DIEN BIEN PROVINCE GENERAL HOSPITAL IN 2024
Main Article Content
Abstract
Background: Pseudomonas aeruginosa is an opportunistic pathogen with intrinsic and acquired resistance to multiple antibiotics, posing a significant challenge in clinical settings. Methods: A cross-sectional study assessed the distribution patterns and antibiotic resistance profiles of P. aeruginosa isolates collected from Dien Bien Province General Hospital in 2024. Results: The prevalence of P. aeruginosa infection was 2.2% (66/3041). The majority of strains were isolated from respiratory specimens (86.36%), and patients aged ≥60 years (60.61%). The highest resistance rates were observed for Piperacillin/Tazobactam (92.4%) and Imipenem (89.4%), while resistance to other tested antibiotics ranged from 77.3% to 86.4%. Conclusion: Although the prevalence of P. aeruginosa infection at Dien Bien Province General Hospital is relatively low, the high levels of antibiotic resistance, underscore the urgent need for continuous antimicrobial resistance surveillance and robust infection control measures
Article Details
Keywords
Pseudomonas aeruginosa, antimicrobial resistance, Dien Bien Province General Hospital.
References
2. Nguyễn Văn An, Nguyễn Văn Đức, Phạm Thị Loan và cộng sự, THỰC TRẠNG KHÁNG KHÁNG SINH CỦA CÁC CHỦNG PSEUDOMONAS AERUGINOSA PHÂN LẬP TẠI BỆNH VIỆN ĐA KHOA TÂM ANH NĂM 2023. Tạp chí Y học Việt Nam, 2024. 542: p. 235-239.
3. Lưu Thị Nga, Lê Văn Hưng, Vũ Huy Lượng và cộng sự, TÌNH HÌNH KHÁNG KHÁNG SINH CỦA PSEUDOMONAS AERUGINOSA PHÂN LẬP ĐƯỢC TẠI BỆNH VIỆN ĐA KHOA QUỐC TẾ HẢI PHÒNG NĂM 2022. Tạp chí Y học Việt Nam, 2024. 537: p. 137-141.
4. Bộ Y tế. Quyết định 26/QĐ-BYT về việc "Hướng dẫn quy trình kỹ thuật chuyên ngành vi sinh y học"2014.
5. Evelina Tacconelli, E.C., Alessia Savoldi Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis2018 Mar;18(3):318-327_17May2025]; Available from: https://doi.org/10.1016/s1473-3099(17)30753-3.
6. Sader, H.S., M. Castanheira, S.J.R. Arends, et al., Geographical and temporal variation in the frequency and antimicrobial susceptibility of bacteria isolated from patients hospitalized with bacterial pneumonia: results from 20 years of the SENTRY Antimicrobial Surveillance Program (1997-2016). 2019 Jun 1_17May2025]; 74(6):1595-1606]. Available from: https://doi.org/10.1093/jac/dkz074.
7. Kay A Ramsay, A.R., Samuel T Wardell, Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complex. 2023 May 16_17May2025]; 18(5):e0285856]. Available from: https://doi.org/10.1371/journal.pone.0285856.
8. Clinical and laboratory standards institute (CLSI), Performance Standards for Antimicrobial Susceptibility Testing, 34th Edition. 2024.