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Date Published: 13/01/2022
Abstract Views: 1567
Views PDF: 671
DOI: https://doi.org/10.51298/vmj.v509i2.1837
Issue
Vol. 509 No. 2 (2021)
Section
Các bài báo
How to Cite
Thị Ngọc Ánh, H. ., Thị Thúy, L. ., Thị Tuyết Thu, H. ., Thị Tuyết, N. ., Thị Hà My, L. ., Quốc Chiến, T. ., Ngọc Sơn, H. ., Đức Minh, H. ., & Vĩnh Niên, L. . (2022). BLOOD URIC ACID LEVELS IN PATIENTS WITH CHRONIC KIDNEY DISEASE IN DA NANG C HOSPITAL. Vietnam Medical Journal, 509(2). https://doi.org/10.51298/vmj.v509i2.1837

BLOOD URIC ACID LEVELS IN PATIENTS WITH CHRONIC KIDNEY DISEASE IN DA NANG C HOSPITAL

Huỳnh Thị Ngọc Ánh1, Lê Thị Thúy1, Hồ Thị Tuyết Thu1, Ngô Thị Tuyết1, Lê Thị Hà My1, Trần Quốc Chiến1, Huỳnh Ngọc Sơn2, Huỳnh Đức Minh3, Lâm Vĩnh Niên4,
1 Danang University of Medical Technology and Pharmacy
2 Da Nang C Hospital
3 Hai Chau District Medical Center, Danang City
4 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Background: Chronic kidney disease reduces uric acid excretion and increases blood uric acid levels. Objectives: Investigation of variation in uric acid concentration in patients with chronic kidney disease. To investigate the relationship and correlation between uric acid levels in patients with chronic kidney disease with some clinical and subclinical. Method: This is a descriptive cross-sectional study on 98 patients, Department of Nephrology – Urology at Da Nang C Hospital from March 2020 to October 2020. Research subjects were performed tests: acid uric, ure, creatinin, GFR, blood count  Collected data were handled by the medical statistical method with the support of Stata 14.0 software. Results: The average acid uric levels was 425,0 ± 118,1 μmol/l and there was significant association with stage of chronic kidney disease (p = 0,029).There was a positive correlation of acid uric levels with ure, creatinine and negative correlation of acid uric levels with GFR (p < 0,05). Conclusion: Blood uric acid levels should be regularly monitored in patients with chronic kidney disease.

Article Details

Keywords

acid uric, chronic kidney disease, ure, creatinin, GFR

References

1. Annual Data Report (2014), "CKD in the United States: An Overview of the USRDS Annual Data Report, Volume 1", 1-9.
2. Nguyễn Văn Tuấn (2015), "Nghiên cứu nồng độ TGF-beta1 Và hs-CRP huyết thanh ở bệnh nhân bị bệnh thận mạn", Luận án Tiến sỹ Y học. Đại học Y Dược Huế.
3. KDIGO (2012), "KDIGO 2012 Clinical practice guideline for the evaluation and management of chronic kidney disease", Kidney International supplements. 3((1)), 5-14.
4. Levey A. S (2009), "A new equation to estimate glomerular filtration rate", Ann Intern Med. 150(9), 604-12.
5. Zhu Y, Pandya B. J Choi H. K (2012), "Comorbidities of gout and hyperuricemia in the US general population: NHANES 2007-2008", Am J Med. 125(7), 679-687.
6. Đỗ Gia Tuyển, Đặng Thị Việt Hà Nguyễn Thị An Thủy (2016), "Tình trạng rối loạn Acid uric máu ở bệnh nhân suy thận mạn chưa điều tri thay thế", Tạp chí nghiên cứu y học. 101(3), 143 - 150.
7. Liu X (2018), "Effects of uric acid-lowering therapy on the progression of chronic kidney disease: a systematic review and meta-analysis", Renal Failure. 40(1), 289-297.
8. Trịnh Kiến Trung (2015), "Nghiên cứu nồng độ acid uric máu, bệnh gout và hội chứng chuyển hóa ở người từ 40 tuổi trở lên tại thành phố Cần Thơ", Luận án Tiến sĩ Y học.