Evaluation of Treatment Outcomes of Keloids Using Surgical Excision Combined with Superficial Radiation Therapy at the National Burns Hospital

Thị Thục Trang Phan1, , Đoàn Tiến Linh Nguyễn1, Trung Quyết Đỗ1, Duy Hoà Khuất1, Tuấn Anh Nguyễn1, Tuấn Anh Vũ1
1 Bệnh viện Bỏng Quốc gia Lê Hữu Trác

Main Article Content

Abstract

Objective: To evaluate the outcomes of keloid treatment using surgical excision combined with superficial radiation therapy (SRT) at the National Burns Hospital Lê Hữu Trác.


Methods: A prospective single-arm clinical intervention study was conducted on 20 keloid patients who underwent surgical excision followed by SRT using the SRT-100 device (Sensus Healthcare, USA) at a total dose of 18 Gy in 3 fractions over 3 consecutive days from January 2025 to December 2025.


Results: Early complication rates were low; 95.0% of patients achieved primary wound healing. The total JSS score decreased from 10.65 ± 2.10 (at 3 months) to 5.30 ± 1.60 (at 12 months) (p < 0.05). Observer POSAS total score decreased from 36.20 ± 5.80 (preoperative) to 18.50 ± 3.50 (at 12 months); Patient POSAS decreased from 31.40 ± 5.20 to 13.40 ± 3.00 (p < 0.05). At 12 months, 85.0% achieved good outcome and 15.0% recurrence. Superficial X-ray-induced hyperpigmentation was common in postoperative keloid radiotherapy (60.0%).


Conclusion: Surgical excision combined with superficial radiation therapy is an effective and safe treatment for keloids, with a low recurrence rate and significant improvement in scar assessment parameters.

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References

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