SURGICAL TREATMENT OF CRANIOFACIAL OSTEOMYELITIS AT CHO RAY HOSPITAL

Hạnh Uyên Trần1, , Anh Bích Trần1, Tri Thức Nguyễn1, Minh Trường Trần1
1 Bệnh viện Chợ Rẫy

Main Article Content

Abstract

Objective: To evaluate the clinical symptoms, causes, and treatment outcomes of 53 cases of necrotizing osteomyelitis at Cho Ray Hospital after the Covid-19 pandemic.


Subjects and methods: The research method was a prospective study of 53 patients: 25 males (47%) and 28 females (53%) with necrotizing osteomyelitis of the craniofacial region at the Department of Otolaryngology, Cho Ray Hospital from August 2021 to August 2023. The main clinical symptoms were persistent dull pain in the face and skull, pus fistule to the skin, maxillary bone mobility, necrotizing and perforation of the palatal bone. Most of patients had concomitant diabetes mellitus and in an unstable upon admission.


Surgery aimed at removing pathological bone and draining abscesses was performed in 49/53 cases using external, endoscopic, or combined approaches. 27 cases used a single surgical approach, 19 cases used two surgical approaches, and 3 cases used three surgical approaches in combination with antibiotics and antifungals. The minimum postoperative follow-up period was one year with no deaths patient.


Results: Except for the first 4 cases that did not undergo surgery and resulted in death. The remaining 49 cases have undergone surgery, have had good results  and were discharged from the hospital.


Conclusion: Necrotizing osteomyelitis is associated with COVID-19, particularly common in individuals with diabetes and weakened immune systems. The condition is easily overlooked due to confusion with common sinusitis. Surgical removal of the necrotic bone combined with medical and antifungal medication treatment yields good results.

Article Details

References

1. Suresh A, Joshi A, Desai AK, et al. Covid-19-associated fungal osteomyelitis of jaws and sinuses: An experience-driven management protocol. Medical mycology. Feb 2 2022;60(2)doi:10.1093/mmy/myab082
2. Said Ahmed WM, Elsherbini AM, Elsherbiny NM, El-Sherbiny M, Ramzy NI, Arafa AF. Maxillary Mucormycosis Osteomyelitis in Post COVID-19 Patients: A Series of Fourteen Cases. Diagnostics (Basel, Switzerland). Nov 5 2021;11(11)doi:10.3390/diagnostics11112050
3. Mañón VA, Balandran S, Young S, Wong M, Melville JC. COVID-Associated Avascular Necrosis of the Maxilla-A Rare, New Side Effect of COVID-19. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. Jul 2022;80(7):1254-1259. doi:10.1016/j.joms.2022.04.015
4. Boymuradov SA, Rustamova DA, Bobamuratova DT, et al. Aspects of maxillar osteomyelitis in patients who had COVID-19 in Uzbekistan. Advances in Oral and Maxillofacial Surgery. 2021 July-September;3:100106. doi: 10.1016/j.adoms.2021.100106. Epub 2021 Jun 7.
5. Gupta G, Gupta D, Gupta P, Gupta N. Osteonecrosis of Jaw as an Oral Manifestation of COVID-19: A Case Report. Acta Scientific Dental Scienecs. 03/06 2021;5:21-25. doi:10.31080/ASDS.2021.05.1059
6. Al-Mahalawy H, El-Mahallawy Y, Dessoky NY, et al. Post-COVID-19 related osteonecrosis of the jaw (PC-RONJ): an alarming morbidity in COVID-19 surviving patients. BMC infectious diseases. Jun 14 2022;22(1):544. doi:10.1186/s12879-022-07518-9
7. Pauli MA, Pereira LM, Monteiro ML, de Camargo AR, Rabelo GD. Painful palatal lesion in a patient with COVID-19. Oral surgery, oral medicine, oral pathology and oral radiology. Jun 2021;131(6):620-625. doi:10.1016/j.oooo.2021.03.010
8. Park JY. Post-acute infection syndrome after COVID-19: effects on the oral and maxillofacial region and the recent publication trends. Journal of the Korean Association of Oral and Maxillofacial Surgeons. Jun 30 2022;48(3):131-132. doi:10.5125/jkaoms.2022.48.3.131