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Issue: Vol. 562 No. 3 (2026)
Section: Các bài báo
DOI: 10.51298/vmj.v562i3.18452
Date Published: 13/08/2026
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Downloads 22
How to Cite
Viên , H. L., Ngô, T. N., Đào , T. T. M., & Nguyễn , D. T. (2026). ASSOCIATION OF HIGH-SENSITIVITY TROPONIN I WITH CLINICAL AND PARACLINICAL CHARACTERISTICS IN PATIENTS WITH ACUTE ISCHEMIC STROKE. Vietnam Medical Journal, 562(3). https://doi.org/10.51298/vmj.v562i3.18452

ASSOCIATION OF HIGH-SENSITIVITY TROPONIN I WITH CLINICAL AND PARACLINICAL CHARACTERISTICS IN PATIENTS WITH ACUTE ISCHEMIC STROKE

Hoàng Long Viên 1,2, , Thúy Ngọc Ngô1,2, Thị Thanh Mai Đào 2, Duy Tuấn Nguyễn 1
1 Viện Tim mạch, Bệnh viện Bạch Mai
2 Trường Đại học Y Dược – Đại học Quốc gia Hà Nội

Main Article Content

Abstract

Methods: A cross-sectional descriptive study was conducted on 60 patients with acute ischemic stroke treated at Bach Mai Hospital. Patients underwent TnI-hs quantification, clinical assessment, Holter ECG monitoring, and brain imaging. 


Results: The prevalence of elevated TnI-hs was 26.7%. TnI-hs levels were significantly associated with age < 75 years (p=0.028) and brainstem infarction (100% of patients with brainstem lesions had elevated TnI-hs, p=0.023). Notably, a strong correlation was observed between TnI-hs and cardiovascular factors: the rate of elevated TnI-hs in patients with a history of heart failure was 4.5 times higher than in those without (85.7% vs. 18.9%; p=0.001); the rate in patients with atrial fibrillation was 42.9%, significantly higher than in the sinus rhythm group (12.5%; p=0.008). For predicting atrial fibrillation, TnI-hs showed an Area Under the Curve (AUC) of 0.752; at a cut-off of >38.05 ng/L, the specificity was 91.2%. 


Conclusion: In acute ischemic stroke patients, elevated TnI-hs is strongly linked to underlying cardiovascular conditions (heart failure, atrial fibrillation) and specific brain lesion locations (brainstem). TnI-hs serves as a valuable biomarker with high specificity for suggesting occult atrial fibrillation.


Objective: To investigate the association between high-sensitivity Troponin I (TnI-hs) levels and clinical and paraclinical characteristics in patients with acute ischemic stroke.

Keywords

Acute ischemic stroke, TnI-hs, Atrial fibrillation

Article Details

References

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