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Issue: Vol. 561 No. 3 (2026)
Section: Các bài báo
DOI: 10.51298/vmj.v561i3.18483
Date Published: 11/08/2026
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How to Cite
Lê, V. Q., Nguyễn, T. T. M., Trương, T. H., & Nguyễn, T. H. (2026). CLINICAL CHARACTERISTICS OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY AT THE INTENSIVE CARE AND TOXICOLOGY DEPARTMENT, PHU THO PROVINCIAL GENERAL HOSPITAL. Vietnam Medical Journal, 561(3). https://doi.org/10.51298/vmj.v561i3.18483

CLINICAL CHARACTERISTICS OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY AT THE INTENSIVE CARE AND TOXICOLOGY DEPARTMENT, PHU THO PROVINCIAL GENERAL HOSPITAL

Văn Quý Lê1, , Thị Thanh Mai Nguyễn1, Thanh Hùng Trương1, Thị Hiền Nguyễn2
1 Bệnh viện Đa khoa tỉnh Phú Thọ
2 Trường Đại học Y dược, Đại học Thái Nguyên

Main Article Content

Abstract

Objective: To describe selected paraclinical characteristics of patients with severe traumatic brain injury (TBI) treated at the Intensive Care and Toxicology Department of Phu Tho Provincial General Hospital.


Subjects and Methods: A cross-sectional descriptive study was conducted on 25 patients with severe TBI at the Intensive Care and Toxicology Department, Phu Tho Provincial General Hospital.


Results: The male-to-female ratio was approximately 4:1. Hematological findings showed leukocytosis (38.0%) and thrombocytopenia (88.0%). Biochemical results revealed hyperglycemia >11 mmol/L (76.0%), elevated AST (80.0%), and elevated ALT (68.0%). Coagulation parameters (APTT, INR, fibrinogen) showed no significant changes. Arterial blood gas analysis indicated a trend toward alkalemia with pH >7.55 (60.0%) and decreased PaCO2 (48.0%). Brain CT scans commonly showed intracerebral hematoma and midline shift, with rates of 56% and 60%, respectively.


Conclusion: Patients with severe TBI were predominantly male, with notable paraclinical abnormalities including hyperglycemia, elevated liver enzymes, thrombocytopenia, and respiratory alkalosis. Basic coagulation parameters remained largely unchanged, reflecting systemic stress response and multi-organ involvement.

Keywords

Severe traumatic brain injury, blood gas, biochemistry, hematology

Article Details

References

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