A STUDY OF ASSOCIATED FACTORS IN SURGICALLY TREATED ORAL CAVITY CANCER AT CHO RAY HOSPITAL FROM 2016 TO 2020

Anh Bích Trần1, , Văn Đô Nguyễn2
1 Bệnh viện Chợ Rẫy
2 Trung tâm Ung bướu, Bệnh viện Chợ Rẫy

Main Article Content

Abstract

Objective: To describe the clinicopathological characteristics and evaluate factors associated with cervical lymph node metastasis in patients with oral cavity cancer treated surgically at Cho Ray Hospital from 2016 to 2020.


Subjects and Methods: A retrospective descriptive study was conducted on 55 patients with oral cavity cancer who underwent surgical resection of the primary tumor with neck dissection. Variables included age, sex, smoking status, alcohol consumption, primary tumor site, TNM stage, histological differentiation, and cervical lymph node status. Associations were analyzed using appropriate statistical tests.


Results: The mean age was 58.3 years (range: 26-81), with a male predominance (76.4%). Most patients were diagnosed at advanced stages (III-IV) (76.4%). The rate of cervical lymph node metastasis was 61.8%. The most common tumor sites were the tongue (60%) and floor of mouth (40%). All cases were squamous cell carcinoma, including 49.1% well-differentiated and 50.9% moderately differentiated tumors. Tumor stage and primary site were associated with cervical lymph node metastasis.


Conclusion: Oral cavity cancer is frequently diagnosed at an advanced stage and is associated with a high rate of cervical lymph node metastasis. Tumor stage and primary site are important factors related to nodal involvement. Early detection and comprehensive cervical evaluation are essential in management.

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References

1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021; 71(3): 209-49. doi:10.3322/caac.21660
2. Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023;73(1):17-48. doi:10.3322/caac.21763
3. Kim KY, Yoon SY, Kim EK, Kim SY. Prognostic factors in oral cavity cancer: analysis of 180 cases. J Korean Assoc Oral Maxillofac Surg. 2013;39(4):171-8. doi:10.5125/jkaoms.2013.39.4.171
4. Zbären P, Lehmann W. Frequency and predictive factors of occult cervical lymph node metastases in early oral cancer. Head Neck. 2007;29(8):731-7. doi:10.1002/hed.20590
5. National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology: Head and Neck Cancers. Version 2.2023. Available from: https://www.nccn.org.