OUTCOMES OF HEPATECTOMY WITH EXTRAHEPATIC BILE DUCT RESECTION FOR THE TREATMENT OF PERIHILAR CHOLANGIOCARCINOMA AT VIET DUC UNIVERSITY HOSPITAL
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Abstract
Objective: To evaluate the outcomes of hepatectomy combined with extrahepatic bile duct resection in patients with perihilar cholangiocarcinoma at Viet Duc University Hospital.
Patients and method: This retrospective descriptive study included 21 patients diagnosed with perihilar cholangiocarcinoma who underwent hepatectomy combined with extrahepatic bile duct resection between January 2015 and December 2022.
Results: The mean age was 61.95 ± 9.74 years, with females accounting for 52.4%. According to the Bismuth–Corlette classification, 52,4% patients were classified type IIIB, 38,1% type IIIA, 4,8% type II, and 4,8% type IV. All patients underwent major hepatectomy combined with extrahepatic bile duct resection: 38.1% patients underwent right hepatectomy with caudate lobectomy, 38.1% underwent left hepatectomy with caudate lobectomy, 14.2% underwent extended left hepatectomy with caudate lobectomy,. R0 resection was achieved in 19 out of 21(90.5%) patients, with no cases of gross residual tumor. Notably, 33,3% patients required vascular resection and reconstruction. Major postoperative complications included liver failure and bile leakage, with rates of 14.3% and 4.8%, respectively. All patients were discharged in stable condition and followed up regularly. There was no 90-day postoperative mortality. The overall survival rates at 1 year and 3 years were 95.24% and 38.1%, respectively.
Conclusion: Liver resection with extrahepatic duct for the treatment of perihilar cholangiocarcinoma achieves a high rate of R0 resection. It was safely performed without postoperative severe complications and mortality, concurrently lengthened the overal survival for patients
Keywords
Klatskin tumor, perihilar cholangiocarcinoma, hepatectomy
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References
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