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Date Published: 13/01/2022
Abstract Views: 388
Views PDF: 291
DOI: https://doi.org/10.51298/vmj.v509i2.1863
Issue
Vol. 509 No. 2 (2021)
Section
Các bài báo
How to Cite
Phước Trung, L. ., Hữu Nghị, Đỗ ., & Đức Hùng, T. . (2022). STUDY ON SERUM NT-proBNP LEVELS AND ASSOCIATION WITH SEVERITY OF CORONARY ARTERY DISEASE ASSESSED BY SYNTAX II SCORE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION. Vietnam Medical Journal, 509(2). https://doi.org/10.51298/vmj.v509i2.1863

STUDY ON SERUM NT-proBNP LEVELS AND ASSOCIATION WITH SEVERITY OF CORONARY ARTERY DISEASE ASSESSED BY SYNTAX II SCORE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

Lê Phước Trung1, Đỗ Hữu Nghị2, Trần Đức Hùng3,
1 Vietnam Military Medical University
2 Ha Dong General Hospital
3 Military Hospital 103

Main Article Content

Abstract

Objectives: To evaluate serum NT-proBNP levels and to investigate the relationship between NT-proBNP and SYNTAX II score, which is a measure of the complexity of coronary artery disease in patients with acute myocardial infarction (MI). Materials and methods: The descriptive cross-sectional study on 69 patients with acute MI, who underwent coronary angiographic examination in Heart Center, Military Hospital 103 from January 2020 to June 2021. Results: The average age was 65.8 ± 11.2 years, male accounted for 76.8%. The serum NT-proBNP levels was 82.2 to 871.5 pg/mL. Median (25th–75th percentiles) was 242.7 pg/mL. Medium NT-proBNP  levels in the group with 2-vessel lesions (310.9 pg/ml) and 3-vessel lesions (746.1 pg/ml) was significantly higher than in the group with 1-vessel lesion (89.2 pg/ml) (p<0.05). Medium NT-proBNP levels in the group with SYNTAX score < 23 (214.8 pg/ml) was significantly lower than in the group with SYNTAX score ≥ 23 (1124.7 pg/ml) (p <0.05). SYNTAX score was positively correlated with serum NT-proBNP levels (r=0.62; p<0.05). The cut-off value of NT-proBNP concentration to predict SYNTAX score ≥ 23 was 496.85 pg/ml, sensitivity 75%, specificity 77.4% (p<0.05). Conclusion: The serum NT-proBNP levels of patients with acute MI were quite strongly correlated with severity of coronary lesions assessed by SYNTAX II score.

Article Details

Keywords

Acute Myocardial Infarction, NT-proBNP, SYNTAX II score

References

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