CHARACTERISTICS OF ELECTROLYTE DISORDERS IN SEVERE BURN PATIENTS WITH SEPSIS COMPLICATIONS

Tuấn Hưng Ngô1,2, , Đình Hùng Trần1,2, Lê Nguyệt Minh Trần3
1 Bệnh viện Bỏng Quốc gia Lê Hữu Trác
2 Học viện Quân y
3 Bệnh viện Quân y 103

Main Article Content

Abstract

Objective: To characterize electrolyte disturbances and assess their impact on mortality in patients with severe burns complicated by sepsis.


Methods: A cross-sectional study was performed in 60 patients with severe burns and sepsis admitted to the Intensive Care Unit of Le Huu Trac National Burn Hospital from January 2023 to June 2024.


Results: At sepsis diagnosis, 85% of patients had at least one electrolyte abnormality. Hypocalcemia (75%) was the most frequent disorder, followed by hypernatremia (43.33%), hypokalemia (41.67%), and hyponatremia (31.67%). Age, deep burn surface area, and serum sodium concentration were independently associated with mortality (all p < 0.05). Each one-year increase in age and each 1% increase in deep burn surface area were associated with a 5% increase in mortality risk, whereas each 1 mmol/L increase in serum sodium concentration was associated with a 3.85-fold higher risk of death.


Conclusions: Hypocalcemia was the predominant electrolyte abnormality, and hypernatremia was independently associated with mortality in patients with severe burns complicated by sepsis. These findings suggest that careful monitoring and correction of serum sodium levels may contribute to improved prognosis.

Article Details

References

1. Yoon J., Kim Y., Kym D. et al. (2017) Subgroup analysis of continuous renal replacement therapy in severely burned patients. PloS one, 12(11):1-11.
2. Namdar T., Siemers F., Stollwerck P. L. et al. (2010) Increased mortality in hypernatremic burned patients. GMS German Medical Science, 8:Doc11.
3. Ebrahim M. K., George A., Bang R. L. (2002) Only some septicaemic patients develop hypernatremia in the burn intensive care unit: why? Burns, 28(6):543-547.
4. Singer M., Deutschman C. S., Seymour C. W. et al. (2016) The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA, 315(8):801-810.
5. Ayrin N. N., Al Faruk A., Alam M. et al. (2025) Electrolyte Disturbances in ICU Patients: Patterns, Predictors, And Outcomes—70 Cases. Clinical Medicine And Health Research Journal, 5(06):1545-1549.
6. Akhter R., Alam M. K., Ghosh S. et al. (2025) Study on serum electrolyte status in sepsis and septic shock patients admitted in Mymensingh Medical College Hospital. TAJ: Journal of Teachers Association, 38(1):262-269.
7. White K. C., Nasser A., Chaba A. et al. (2025) Hypernatremia of critical illness. Journal of Translational Critical Care Medicine, 7(1):e24-00039.
8. Güçyetmez B., Ayyildiz A. C., Ogan A. et al. (2014) Dysnatremia on intensive care unit admission is a stronger risk factor when associated with organ dysfunction. Minerva Anestesiol, 80(10):1096-1104.