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Issue: Vol. 563 No. 1 (2026)
Section: Các bài báo
DOI: 10.51298/vmj.v563i1.18915
Date Published: 15/09/2026
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Mông, T. K. T., Lại, T. T. T., & Phan, N. L. A. (2026). PRELIMINARY RESULTS OF ASSESSING THE MEAN VALUE OF IMMATURE GRANULOCYTES (IG) IN PATIENTS WITH SEPSIS AT BECAMEX INTERNATIONAL HOSPITAL. Vietnam Medical Journal, 563(1). https://doi.org/10.51298/vmj.v563i1.18915

PRELIMINARY RESULTS OF ASSESSING THE MEAN VALUE OF IMMATURE GRANULOCYTES (IG) IN PATIENTS WITH SEPSIS AT BECAMEX INTERNATIONAL HOSPITAL

Thị Kiều Trúc Mông1,2, , Thị Thanh Thảo Lại1, Nguyễn Liên Anh Phan1,3
1 Đại học Y Dược thành phố Hồ Chí Minh
2 Bệnh viện Quốc Tế Becamex
3 Bệnh viện Nhi Đồng 1

Main Article Content

Abstract

Background: Sepsis is a severe infectious condition associated with high mortality. Immature granulocytes (IG) have been considered an early, readily available, and low-cost biomarker.


Objectives: To evaluate the value of immature granulocyte indices and their association with selected inflammatory markers in hospitalized patients with sepsis at Becamex International Hospital.


Materials and methods: A cross-sectional descriptive study was conducted on 19 patients aged ≥18 years who were diagnosed with sepsis according to Sepsis-3 criteria and treated as inpatients from July 2025 to December 2025.


Results: The median age of patients was 65 (52–80) years, with 63.2% aged ≥60 years. The blood culture positivity rate was 57.9%, with Gram-negative bacteria predominating, mainly Escherichia coli. The median IG# was 0.23 (0.13–1.04), and the median IG% was 1.7 (0.94–2.84), showing a right-skewed distribution. IG# showed a very strong positive correlation with procalcitonin (PCT) (r = 0.812; p = 0.05), while no significant correlation was observed with white blood cell count (WBC) or C-reactive protein (CRP). IG% showed a tendency toward correlation with PCT but did not reach statistical significance.


Conclusion: Immature granulocytes, particularly IG#, may serve as a useful adjunct for early diagnosis and assessment of sepsis severity; however, further studies with larger sample sizes are warranted.

Keywords

Sepsis, Immature granulocytes (IG), Procalcitonin, C-reactive protein

Article Details

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