EARLY OUTCOMES OF URETERAL STONE TREATMENT BY URETEROSCOPIC LASER LITHOTRIPSY WITH PROPHYLACTIC ANTIBIOTICS AT CAN THO CENTRAL GENERAL HOSPITAL AND CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL 2025 - 2026
Main Article Content
Abstract
Background: Ureteral calculi are a common urological disorder. Laser ureteroscopic lithotripsy (URS) is a minimally invasive and highly effective treatment modality widely used in current practice. However, postoperative urinary tract infection (UTI) remains a potential complication following endourological intervention. UTIs exhibit a broad clinical spectrum, ranging from asymptomatic bacteriuria to complicated infections; therefore, perioperative antibiotic prophylaxis is recommended.
Objective: To evaluate the early outcomes of ureteroscopic laser lithotripsy for ureteral stones in patients receiving perioperative antibiotic prophylaxis.
Materials and methods: A prospective descriptive study with analytical components was conducted on 33 patients with ureteral calculi who underwent ureteroscopic lithotripsy and received preoperative antibiotic prophylaxis at Can Tho Central General Hospital and Can Tho University of Medicine and Pharmacy Hospital from August 2025 to February 2026.
Results: A total of 33 patients were included, with 57.6% being male and a mean age of 50.8 ± 9.9 years. The most common presenting symptom was dull flank pain (72.7%). Stones were predominantly located in the upper third of the ureter (57.6%). The median stone size was 10.0 mm (IQR: 8.5–11.5). Median operative time was 30 minutes (IQR: 30–40), and median postoperative hospital stay was 1 day (1–1). All patients underwent JJ stent placement. No early postoperative complications were observed (modified Clavien–Dindo grade 0: 100%). The stone-free rate was 97%. Postoperatively, 100% of patients had no symptomatic UTI, and 60.6% demonstrated negative leukocyturia at follow-up.
Conclusion: Laser ureteroscopic lithotripsy with perioperative antibiotic prophylaxis is a safe and effective treatment for ureteral calculi, associated with a low rate of early postoperative complications and a reduced incidence of symptomatic urinary tract infections.
Keywords
Antibiotic prophylaxis, ureteral calculi, ureteroscopy, urinary stones, endourology
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References
2. Đồng Minh Lý, Đàm Văn Cương. Đánh giá kết quả điều trị sỏi niệu quản bằng phương pháp tán sỏi nội soi ngược dòng sử dụng năng lượng laser Holmium: YAG tại Bệnh viện Trường Đại học Y Dược Cần Thơ năm 2021-2022. Tạp chí Y Dược học Cần Thơ. 2022; 50: 77-85.
3. Nguyễn Hữu Nghị, Trương Công Thành, Nguyễn Trung Hiếu. Đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị sỏi niệu quản trên bệnh nhân suy thận bằng phương pháp tán sỏi nội soi ngược dòng sử dụng năng lượng laser tại Bệnh Viện Trường Đại Học Y Dược Cần Thơ Và Bệnh Viện Đa Khoa Trung Ương Cần Thơ năm 2023-2024. Tạp chí Y Dược học Cần Thơ. 2024; 77: 177-183.
4. Trần Thái Phúc, Lại Ngọc Thắng. Kết quả nội soi ngược dòng tán sỏi niệu quản 1/3 giữa và 1/3 dưới sử dụng năng lượng laser-Holmium tại Bệnh Viện Đại Học Y Thái Bình. Tạp Chí Y Học Cộng Đồng. 2025; 66(1): 279-274.
5. Bartoletti R, Cai T, Perletti G, Maxia R, Brugnolli A, et al. Multi-centre observational study of the role of bacterial stone culture in predicting post-operative urosepsis. World Journal of Urology. 2022; 40: 1875-1882.
6. Bonkat G, Bartoletti R, Bruyère F, Cai T, Geerlings SE. EAU Guidelines on Urological Infections. European Association of Urology; 2024
7. Du Z , Sun H, Zhang Y, Cui L, Hou J, Chen J, Chen S, Qiao L. Effectiveness of prophylactic antimicrobial levofloxacin against post-ureteroscopic lithotripsy infection: a multicenter prospective open-label randomized controlled trial. Medicine (Baltimore). 2023; 102(14): e33364.
8. Pischetola A, Hughes T, Geraghty R, Boulmani M, Somani BK. Incidence of urinary infections and urosepsis after ureteroscopy for stone disease: a systematic review of the literature. Therapeutic Advances in Urology. 2025; 18: 17562872251412050.