ĐẶC ĐIỂM BỆNH LÝ THẦN KINH NGOẠI BIÊN VÀ CÁC YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN NGHIỆN RƯỢU MẠN TÍNH

Abstract

Objective: To describe the characteristics of peripheral neuropathy and to analyze associated factors in patients with chronic alcohol dependence.

Subjects and methods: A cross-sectional descriptive study with analytical components was conducted on 64 patients with chronic alcohol dependence treated at Military Hospital 103 between November 2023 and December 2025. Peripheral neuropathy was diagnosed based on the presence of compatible symptoms together with at least one objective neurological sign on clinical examination.

Results: The prevalence of peripheral neuropathy was 53.1%. The most common manifestations were numbness/paresthesia of the lower limbs (94.1%), reduced or absent ankle reflexes (82.4%), and impaired vibration sensation (76.5%). Neuropathy was predominantly sensory in nature and symmetrically involved the lower limbs. Multivariable logistic regression analysis identified alcohol use for ≥10 years (OR = 4.12; 95% CI: 1.35–12.56) and mean corpuscular volume (MCV) >100 fL (OR = 3.29; 95% CI: 1.10–9.84) as independent factors associated with peripheral neuropathy.

Conclusion: Peripheral neuropathy is common among patients with chronic alcohol dependence, predominantly presenting as symmetrical sensory involvement of the lower limbs. Prolonged alcohol use and elevated MCV were independently associated with peripheral neuropathy.