PREVALENCE OF NEONATAL RESPIRATORY FAILURE FOLLOWING CESAREAN SECTION FROM 35 WEEKS GESTATION IN TAM ANH HOSPITAL HO CHI MINH CITY AND RELATED FACTORS
Main Article Content
Abstract
Background: Respiratory distress is a leading cause of mortality in neonates and is more common with increasing rates of cesarean section. In Vietnam, there are still limited reports on neonatal respiratory distress following cesarean delivery.
Objectives: To determine the prevalence and related factors of early neonatal respiratory distress following cesarean section at ≥ 35 weeks of gestation.
Methods: A prospective case–control study was conducted on 257 neonates delivered by cesarean section at ≥ 35 weeks of gestation, including 57 newborns with early respiratory distress within the first 24 hours after birth requiring respiratory support for more than 2 hours, and 200 healthy newborns. Logistic regression analysis was used to identify associated factors.
Results: The rate of early respiratory distress was 3,8% among all cesarean-delivered infants from 01/09/2023 to 30/07/2024. Factors associated with respiratory distress included maternal cesarean section under general anesthesia (OR = 3.36; 95% CI: 1.38–8.14) and lower gestational age (OR = 0.49; 95% CI: 0.36–0.69), specifically 35–36 weeks (OR = 9.58; 95% CI: 3.35–27.38) and 37–38 weeks (OR = 2.07; 95% CI: 1.02–4.18).
Conclusion: The rate of neonatal respiratory distress following cesarean section was 3,8%. This rate was higher when the mother had general anesthesia and when gestational age was lower. Therefore, appropriate management of cesarean delivery and the development of suitable monitoring guidelines at obstetric and neonatal centers are necessary.
Keywords
Neonatal respiratory distress, transient tachypnea of the newborn, cesarean section, elective cesarean, general anesthesia
Article Details
References
2. Cocchi, E., et al. Impact of general vs. neuraxial anesthesia on neonatal outcomes in non-elective cesarean sections. Front Pediatr, 2025. 13: p. 1518456
3. Jis Thomas, Tawa Olayemi Olukade, Aliya Naz et al. The neonatal respiratory morbidity associated with early term caesarean section – an emerging pandemic. J. Perinat. Med. 2021; 49(7): 767–772.
4. Julia Gromann, Sabella Mancinob, Gwendolin Manegold-Brauer et al. Incidence of neonatal respiratory morbidity after vaginal and caesarean delivery in the late-preterm and term period – a retrospective cohort study. Swiss Med Wkly. 2024;154:3798.
5. Shi, X., et al. Perinatal outcome of emergency cesarean section under neuraxial anesthesia versus general anesthesia: a seven-year retrospective analysis. BMC Anesthesiol. 2024; 24(1): p. 33.
6. Tricia Lacy Gomella. Transient tachypnea of the newborn. GOMELLA’S NEONATOLOGY Management, Procedures, On-Call Problems, Diseases, and Drugs, McGraw-Hill, 2020. pp. 1107 – 1114.
7. Tutdibi E, Gries K, Bücheler M, et al. Impact of labor on outcomes in transient tachypnea of the newborn: population-based study. Pediatrics. 2010; 125 (3): e577–e583.