KẾT QUẢ BƯỚC ĐẦU CẮT CƠ THỰC QUẢN QUA NỘI SOI ĐƯỜNG MIỆNG (POEM) ĐIỀU TRỊ CO THẮT TÂM VỊ TẠI BỆNH VIỆN TÂM ANH HÀ NỘI

Abstract

Background: Per oral endoscopic myotomy (POEM) is a novel, minimally invasive endoscopic treatment option for patients with achalasia and is being more widely used all over the world. It has been reported as an effective and safe salvage therapy for achalasia.

Objective: To evaluate the efficacy and safety of per oral endoscopic myotomy (POEM) in patients with achalasia

Methods: This prospective descriptive study included 37 patients with achalasia who underwent POEM from December 2021 to April 2026 at Tam Anh Hospital, Ha Noi. Objective parameters including high-resolution manometry, timed barium swallow, and esophagogastroduodenoscopy were assessed preprocedure and postprocedure. We collected all data including symptoms (Eckardt score), procedure time, length of hospital stay, and adverse events. Clinical success was defined as an Eckardt score ≤ 3.

Results: A total of 37 patients with achalasia underwent POEM. 12/37 (32,43%) had undergone previous treatment (8 pneumatic dilation and 4 Heller myotomy). The mean age was 44,56 (21-83) years. Pre-procedure and post-procedure mean Eckardt scores were 7,0 ± 2,1 (4-12) and 1,02 ± 0,49 (0-3), respectively. POEM was completed successfully in 37/37 (100%) patients with a mean procedure time of 96,2 minutes (range, 41-196 min). Clinical response was observed in 37/37 (100%) patients during a mean follow-up duration of 16,2 months (1,3-38,4 months). The mean length of hospital stay was 3,54 days (range, 3-6 days). No major procedure-related adverse events were observed, and no surgery was needed.

Conclusion: POEM is a safe and effective endoscopic treatment for patients with achalasia including treatment naive and previously treated patients in centers that are experienced in advanced endoscopic techniques.