RISK FACTORS AND CORONARY ARTERY CALCIFICATION ON 256 SLIDE CT-SCANNER

Nguyễn Đình Minh1,, Hoàng Văn Hậu2, Nguyễn Thanh Vân1
1 Vietnam-Germany Friendship Hospital
2 Hanoi Medical University

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Abstract

Objectives: study some risk factors related to coronary artery calcification (CAC) on CT-256 slices. Subjects and methods: a cross-sectional descriptive study of coronary angiogram on CT 256 slices from March to July 2021. Results: total 545 patients, including 261 male and 264 female. Median age was 72 years (63-79), from 39 to 100 years old; in which the median age of male is 71 years old (60-79) lower than that of female, 73 years old (65-80) (p<0.01). Regarding the risks, men were more likely to drink alcohol (24.1%) than women (1.8%) with an odds ratio: 17.8 [95% CI: 7.0-44.9] (p<0.01). On the other hand, the percentage of men who smoking (20.3%) was also higher than that of women (2.1%) with odds ratio: 11.8 [95%CI =5.0-28.0 ] (p<0.01). On CT 256 slices, there were 341 patients with CAC, accounting for 62.6%. The incidence of CAC in 60-years-old and over group (70.2%) was higher than in the younger group (31.1%) (p<0.01), multivariable regression odds ratio was 6,0 [95%CI: 3.7 – 9.9] (p<0.01). Men had a higher rate of CAC (67%) than women (58.5%) (p=0.04), in which the odds ratio of multivariable regression was 1.8 [95%CI: 1 ,2-2,7] (p<0.01). Moreover, the hypertensive patients had a higher rate of CAC (69.4%) than the nortensive group (55.8%), the univariate odds ratio was 1.8 [1.3- 2.5] (p<0.01), and the prevalence of CAC in diabetic patients (74%) was higher than in patients without diabetes (60.1%) with univariate odds ratio of 1,8 [1,2-3,1] (p=0.01). However, these two factors were not found to be significantly related to CAC in the results of multivariable regression analysis (p>0.05). Conclusion: Coronary artery calcification is significantly related to age, gender, high blood pressure and diabetes.

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References

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