VALUE OF THE DECAF SCORE IN PREDICTING ADVERSE IN-HOSPITAL OUTCOMES IN PATIENTS WITH ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT LONG AN GENERAL HOSPITAL
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Abstract
Objective: To evaluate the predictive value of the DECAF score for adverse in-hospital outcomes in patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease (AECOPD).
Methods: This prospective observational study included 108 patients hospitalized with AECOPD at Long An General Hospital between January 2025 and May 2026. The DECAF score was calculated at hospital admission.
Results: The mean age was 69.4 ± 9.8 years, and 75.9% of the patients were male. The median DECAF score was 2 (IQR, 1–3), with 35 patients (32.4%) having a DECAF score ≥3. Adverse in-hospital outcomes occurred in 30 patients (27.8%), and 10 patients (9.3%) died during hospitalization. The proportion of patients with adverse outcomes increased progressively with increasing DECAF scores (p for trend <0.001). The DECAF score was significantly higher in patients with adverse outcomes than in those without adverse outcomes [3 (IQR, 2–4) vs. 1 (IQR, 1–2), p<0.001]. The area under the ROC curve for predicting adverse in-hospital outcomes was 0.842 (95% CI, 0.763–0.921; p<0.001). At a cutoff of ≥3 points, the DECAF score yielded a sensitivity of 70.0% and a specificity of 82.1%.
Conclusion: Higher DECAF scores were associated with a greater frequency of adverse in-hospital outcomes in patients hospitalized with AECOPD. The DECAF score showed good discrimination for adverse outcomes and may complement routine clinical and laboratory assessment for early risk stratification.
Keywords
Chronic obstructive pulmonary disease, acute exacerbation, DECAF score, adverse outcome
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References
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