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Issue: Vol. 563 No. 3 (2026)
Section: Các bài báo
DOI: 10.51298/vmj.v563i3.19172
Date Published: 08/10/2026
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How to Cite
Nguyễn, T. Â., Hồ, T. C., Võ, L. Đ. T., Nguyễn, T. M. Q., Nguyễn, T. A. Đ., Trần, Đ. P., Huỳnh, C. C., Nguyễn, T. T. L., & Lê, T. H. (2026). EVALUATION OF SURGICAL SITE INFECTION RATES AND PREDICTIVE FACTORS IN ONE-STAGE HYPOSPADIAS REPAIR WITHOUT PROLONGED ANTIBIOTIC PROPHYLAXIS. Vietnam Medical Journal, 563(3). https://doi.org/10.51298/vmj.v563i3.19172

EVALUATION OF SURGICAL SITE INFECTION RATES AND PREDICTIVE FACTORS IN ONE-STAGE HYPOSPADIAS REPAIR WITHOUT PROLONGED ANTIBIOTIC PROPHYLAXIS

Tài Ân Nguyễn1,2, , Trung Cường Hồ1,2, Lê Đức Trọng Võ1, Trần Minh Quỳnh Nguyễn1, Thị Anh Đào Nguyễn1, Đại Phú Trần1, Công Chấn Huỳnh1, Thị Trúc Linh Nguyễn2, Thanh Hùng Lê1
1 Khoa Ngoại Thận Tiết Niệu, Bệnh viện Nhi Đồng 1
2 Trường Y, Đại học Y Dược Thành phố Hồ Chí Minh

Main Article Content

Abstract

Background: Prolonged postoperative antibiotic prophylaxis after hypospadias repair remains common despite limited evidence of benefit and growing concerns regarding antimicrobial resistance.


Objective: To evaluate surgical site infection (SSI) and reoperation rates following discontinuation of prolonged postoperative antibiotics in primary single-stage hypospadias repair.


Methods: A retrospective case series was conducted at Children’s Hospital 1 between January 2023 and July 2025. A total of 272 boys undergoing primary single-stage urethroplasty were included. All patients received a single preoperative antibiotic dose. The primary outcome was SSI; the secondary outcome was reoperation for postoperative complications. Multivariable regression analysis was performed to identify independent predictors.


Results: SSI rates were not significantly different between the prolonged antibiotic group and the no-antibiotic group (14.9% vs. 9.9%, p=0.216). Reoperation rates were also comparable (17.7% vs. 19%, p=0.805). Multivariable analysis showed no independent association between postoperative antibiotic use and SSI (p=0.138) or reoperation (p=0.739). Patient age and neourethral length were identified as independent predictors of postoperative outcomes.


Conclusions: Discontinuation of prolonged postoperative antibiotic prophylaxis after primary single-stage hypospadias repair may be safe and does not increase the risk of SSI or reoperation. These findings support antimicrobial stewardship in pediatric urologic surgery.

Keywords

Hypospadias, antibiotic prophylaxis, surgical site infection, urethroplasty, antimicrobial stewardship

Article Details

References

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