FACTORS ASSOCIATED WITH OCCLUSION MYOCARDIAL INFARCTION IN PATIENTS WITH NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AT NGUYEN TRI PHUONG HOSPITAL
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Abstract
Background: A substantial proportion of patients with non-ST-segment elevation myocardial infarction (NSTEMI) have acute occlusion of the culprit coronary artery. Early identification of factors associated with occlusion myocardial infarction (OMI) may facilitate timely invasive coronary angiography and coronary reperfusion.
Objective: To identify clinical, laboratory, and echocardiographic factors associated with OMI in patients with NSTEMI.
Methods: This cross-sectional study used a combined retrospective and prospective data collection approach and included 192 patients aged 18 years or older who were diagnosed with NSTEMI and underwent invasive coronary angiography between December 2024 and June 2026 at the Department of Interventional Cardiology, Nguyen Tri Phuong Hospital. Patients were classified into OMI and non-OMI groups according to coronary angiographic findings and the study criteria. Associated factors were evaluated using univariable and multivariable logistic regression analyses adjusted for age.
Results: Among 192 patients, 88 had OMI, accounting for 45.8%. Compared with the non-OMI group, patients with OMI had higher proportions of obesity (55.7% vs. 27.9%), smoking (75.0% vs. 48.1%), chest pain (85.2% vs. 73.1%), and regional wall motion abnormalities on echocardiography (77.3% vs. 51.0%). High-sensitivity cardiac troponin I concentrations at the measured time points were also significantly higher in the OMI group. In the multivariable logistic regression model, factors independently associated with OMI included obesity (adjusted OR, 2.87; 95% CI, 1.41–5.84; p = 0.004), smoking (adjusted OR, 3.07; 95% CI, 1.49–6.31; p = 0.002), regional wall motion abnormalities (adjusted OR, 4.56; 95% CI, 2.11–9.83; p < 0.001), and each one-class increase in Killip classification (adjusted OR, 1.53; 95% CI, 1.07–2.19; p = 0.019).
Conclusion: OMI was present in nearly half of patients with NSTEMI undergoing invasive coronary angiography. Obesity, smoking, regional wall motion abnormalities on echocardiography, and Killip class were independently associated with OMI.
Keywords
Non-ST-segment elevation myocardial infarction, occlusion myocardial infarction
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References
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