KẾT QUẢ LÂM SÀNG CỦA CÁC TRƯỜNG HỢP CHUYỂN MỘT PHÔI NANG QUA PHƯƠNG PHÁP NUÔI CẤY TIME LAPSE TẠI TRUNG TÂM HỖ TRỢ SINH SẢN VINMEC TIMES CITY

Abstract

Objective: Analysis of the association between abnormal morphokinetics of early embryos and clinical outcomes. Materials and Methods: the study conducted on 88 frozen embryo transfer cycles, with only 1 blastocyst. Blastocysts were made from ICSI cycles and cultured by timelapse system. Patients were evaluated for pregnancy outcomes by βhcg testing on day 14 post-embryo transfer and follow-up ultrasound until the ongoing pregnancy, at 10 weeks. Results: the βhcg (+) rate, the clinical pregnancy rate, the ongoing pregnancy rate were 62,5%, 55,7%, 51,1% respectively. The pregnancy rate of the group without abnormality in division were higher than that in the group with abnormality at 2 stages of division, the βhcg (+) rate (67% vs 51%), the clinical pregnancy rate  (61% vs 41%), and the ongoing rate (56% vs 37%), the difference is no significant. There was no case of pregnancy after embryo transfer with vaculation in blasomere. Conclusion: embryos that did not appear abnormal division during the early stage of development will have a better pregnancy outcome than embryos with abnormalities present twice. However, studies with larger sample sizes are needed to obtain more reliable results.