GROSS-TOTAL RESECTION RATE OF PETROCLIVAL MENINGIOMAS VIA THE ANTERIOR TRANSPETROSAL APPROACH

Đình Hưởng Nguyễn1, , Mạnh Hùng Ngô2, Đình Hùng Kiều1,3
1 Trường Đại học Y Hà Nội
2 Bệnh viện Đại học Y Dược - Đại học Quốc gia Hà Nội
3 Hệ thống y tế Vietlife

Main Article Content

Abstract

Objective: To determine the gross-total resection (GTR) rate on early postoperative contrast-enhanced magnetic resonance imaging (MRI) in patients with petroclival meningioma operated on through the anterior transpetrosal approach.


Subjects and methods: A consecutive descriptive case series combining retrospective and prospective data collection in 32 patients operated on at Viet Duc University Hospital between January 2020 and December 2025. GTR was defined as the absence of nodular or mass-like enhancing tissue at the preoperative tumour site on contrast-enhanced MRI obtained 24–72 hours after surgery. The proportion is reported with a 95% Wilson confidence interval (CI).


Results: Mean age was 53.5 ± 12.9 years; 78.1% were female. Mean maximal tumour diameter was 33.2 ± 14.2 mm; 40.6% invaded the cavernous sinus. GTR was achieved in 20/32 patients (62.5%; 95% CI: 45.3–77.1%); residual tumour was present in 12/32 (37.5%). By intraoperative Simpson grading, Simpson I–II was 53.1% and Simpson I–III was 68.8%. GTR was highest in the petrous apex subtype (9/11) and lowest in the cavernous sinus subtype (1/5).


Conclusion: In this selected series, the MRI-defined GTR rate was 62.5%, with a wide confidence interval reflecting the small sample. The estimate should be interpreted in the context of patient selection and a maximal safe resection policy.

Article Details

References

1. Phạm Duy. Nghiên cứu chẩn đoán và điều trị vi phẫu thuật u màng não góc cầu – tiểu não. Luận án Tiến sĩ Y học, Trường Đại học Y Hà Nội; 2023.
2. Agha RA, Mathew G, Rashid R, et al. Revised Preferred Reporting of Case Series in Surgery (PROCESS) guideline: an update for the age of artificial intelligence. Premier J Sci. 2025;10:100080.
3. Almefty R, Dunn IF, Pravdenkova S, et al. True petroclival meningiomas: results of surgical management. J Neurosurg. 2014;120(1):40-51.
4. Cheng Y, Song Y, Yang W, et al. The evolution of anterior transpetrosal approach for the treatment of petroclival meningiomas: a single-center 128-case experience. World Neurosurg. 2024;181:e35-e44.
5. Di Carlo DT, Capo G, Fava A, et al. Petroclival meningiomas: the risk of post-operative cranial nerve deficits among different surgical approaches – a systematic review and meta-analysis. Acta Neurochir (Wien). 2020;162(11):2695-2709.
6. DiLuna ML, Bulsara KR. Surgery for petroclival meningiomas: a comprehensive review of outcomes in the skull base surgery era. Skull Base. 2010;20(5):337-342.
7. Giammattei L, Starnoni D, Levivier M, et al. Petroclival meningiomas: update of current treatment and consensus by the EANS skull base section. Acta Neurochir (Wien). 2021;163(6):1639-1663.
8. Ichimura S, Kawase T, Onozuka S, et al. Four subtypes of petroclival meningiomas: differences in symptoms and operative findings using the anterior transpetrosal approach. Acta Neurochir (Wien). 2008;150(7):637-645.
9. Kawase T, Shiobara R, Toya S. Anterior transpetrosal-transtentorial approach for sphenopetroclival meningiomas: surgical method and results in 10 patients. Neurosurgery. 1991;28(6):869-875.
10. Lin Y, Gao Q, Jin H, et al. Analysis of approaches in the microsurgical treatment of 102 cases of petroclival meningioma in a single center. Front Neurol. 2021;12:627736.
11. Natarajan SK, Sekhar LN, Schessel D, et al. Petroclival meningiomas: multimodality treatment and outcomes at long-term follow-up. Neurosurgery. 2007;60(6):965-979.
12. Pham HN, Dong HV, Duong HD, et al. Early surgical outcome of petroclival meningiomas: a single-center case series from Vietnam. Interdiscip Neurosurg. 2025;41:102086.