KẾT QUẢ ĐIỀU TRỊ BỆNH VIÊM TỤY CẤP Ở TRẺ EM TẠI BỆNH VIỆN NHI THANH HÓA

Abstract

Background: Acute pancreatitis is a condition characterized by pancreatic cell injury caused by autodigestion from pancreatic enzymes, ranging in severity from mild to severe, with necrotizing pancreatitis that may be fatal if not treated promptly.

Aims: Evaluation of treatment outcomes of acute pancreatitis in children at Thanh Hoa children’s hospital.

Materials and Methods: A case series study was conducted on 51 patients diagnosed with acute pancreatitis according to the 2012 Revised Atlanta Classification and treated at the Department of Gastroenterology, Thanh Hoa Children’s Hospital.

Results: Among the 51 pediatric acute pancreatitis, the male-to-female ratio was 1.3:1, 74.5% accounted for mild severity and 68.5% without identified etiology. Patients in moderate and severe groups had longer hospital stays (7.77 ± 2.09 vs. 5.92 ± 2.07 days, p = 0.008) and higher antibiotic use (100% vs. 13.1%, p < 0.001) than those in mild group. At the time of discharge, serum amylase and lipase levels had normalized in 84.3% and 30.2% of the pediatric patients, respectively.  Complete recovery occurred in 51.0%, recurrence in 35.3%, and 11.7% were transferred for surgery.

Conclusion: Most cases of pediatric acute pancreatitis were mild and responded well to conservative treatment. Moderate and severe groups required more antibiotic therapy and longer hospitalization. Overall outcomes were favorable, though the recurrence rate warrants long-term follow-up.