ASSOCIATION BETWEEN MIDDLE CEREBRAL AND UMBILICAL ARTERY DOPPLER INDICES AND PERINATAL OUTCOMES IN POSTDATE PREGNANCIES AT VINMEC TIMES CITY INTERNATIONAL GENERAL HOSPITAL

Quang Nam Nguyễn1,2, , Thị Thu Hương Hoàng1, Thị Mai Nguyễn3, Ngọc Hà Phạm4, Ngọc Quyền Đào4
1 Bệnh viện Đa khoa Quốc tế Vinmec Times City
2 Trường Đại học VinUni
3 Bệnh viện Đa khoa Quốc tế Vinmec Phú Quốc
4 Bệnh viện Đa khoa Quốc tế Vinmec Ocean Park 2

Main Article Content

Abstract

Objective: To evaluate the relationship between Doppler indices of the middle cerebral artery (MCA), umbilical artery (UA), cerebroplacental ratio (CPR), and perinatal outcomes in postdate pregnancies.


Subjects and Methods: A cross-sectional analytical study was conducted among 66 women with singleton live pregnancies at 40 weeks and 1 day to 41 weeks and 6 days of gestation. Umbilical artery (UA) and middle cerebral artery (MCA) Doppler ultrasonography was performed before pregnancy termination at Vinmec Times City International General Hospital between January and December 2025.


Results: Fourteen of 66 pregnancies (21.2%) had at least one adverse perinatal outcome. Compared with those without adverse outcomes, middle cerebral artery (MCA) PI, MCA RI, and the cerebroplacental ratio (CPR) were significantly lower in pregnancies with adverse outcomes (p=0.008, p=0.021, and p=0.003, respectively), whereas umbilical artery (UA) Doppler indices did not differ significantly between the groups. The areas under the curve (AUCs) for MCA PI and CPR were 0.780 (95% CI, 0.640–0.920) and 0.760 (95% CI, 0.620–0.900), respectively, with corresponding optimal cut-off values of ≤1.18 and ≤1.43. MCA PI ≤1.18 and CPR ≤1.43 were associated with cesarean delivery for fetal distress, with odds ratios (ORs) of 5.60 (95% CI, 1.34–23.39; p=0.018) and 5.20 (95% CI, 1.30–20.76; p=0.019), respectively.


Conclusion: Reduced MCA PI and CPR were associated with adverse perinatal outcomes in postdate pregnancies. MCA and CPR Doppler assessment may provide additional information for fetal surveillance and clinical management.

Article Details

References

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