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Issue: Vol. 567 No. 1 (2026)
Section: Các bài báo
DOI: 10.51298/vmj.v567i1.19263
Date Published: 05/11/2026
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Downloads 22
How to Cite
Quách, P. H., Ngô, V. T., Quảng, T. N., Nguyễn, T. K. H., & Đặng, C. H. (2026). EVALUATION OF ADVERSE REACTIONS IN PLATELETPHERESIS DONORS AT THE BLOOD TRANSFUSION AND HEMATOLOGY HOSPITAL. Vietnam Medical Journal, 567(1). https://doi.org/10.51298/vmj.v567i1.19263

EVALUATION OF ADVERSE REACTIONS IN PLATELETPHERESIS DONORS AT THE BLOOD TRANSFUSION AND HEMATOLOGY HOSPITAL

Phước Hòa Quách1, , Văn Tân Ngô1, Trọng Nhân Quảng1, Thị Kim Hằng Nguyễn1, Chí Hiếu Đặng1
1 Bệnh viện Truyền máu Huyết học

Main Article Content

Abstract

Objectives: To determine the incidence and identify factors associated with adverse reactions in plateletpheresis donors at the Blood Transfusion and Hematology Hospital (BTHH).


Study design: A cross-sectional descriptive study. Adverse reactions were classified according to ISBT/AABB/IHN 2014 standards; univariate and multivariate logistic regression analyses were used to identify risk factors.


Setting and time: Donor Selection Department, BTHH, from November 2025 to April 2026.


Subjects: 1,495 plateletpheresis donors at the Donor Selection Department, BTHH, during the study period.


Results: The overall incidence of adverse reactions was 6.7% (100/1,495), predominantly mild to moderate; citrate-related reactions were the most common (54%), followed by systemic reactions (26%) and local reactions (20%). Multivariate analysis identified five independent risk factors for overall adverse reactions: female sex (OR=2.41), age ≤25 (OR=2.24), first-time donors (OR=2.43), BMI<23 (OR=1.71), and prolonged apheresis duration (OR=2.41), with p<0.05.


Conclusions: Plateletpheresis donation at BTHH was highly safe, with citrate reactions being the most common. Female sex, age ≤25, first-time donation, BMI<23 and apheresis duration >100 minutes increased the odds of adverse reactions by 1.71 to 2.43 times; apheresis duration >100 minutes increased the odds of citrate reactions by 4.75 times.

Keywords

Plateletpheresis, adverse reactions, risk factors

Article Details

References

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