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Issue: Vol. 567 No. 1 (2026)
Section: Các bài báo
DOI: 10.51298/vmj.v567i1.19308
Date Published: 05/11/2026
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Nguyễn, T. T. D., Trần, V. C., & Trần, N. Q. (2026). CONFIRMATORY TESTING RESULTS OF HEPATITIS B VIRUS INFECTION AMONG BLOOD DONORS WITH REACTIVE SCREENING RESULTS AT THE NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION OVER A 5-YEAR PERIOD (2020–2024). Vietnam Medical Journal, 567(1). https://doi.org/10.51298/vmj.v567i1.19308

CONFIRMATORY TESTING RESULTS OF HEPATITIS B VIRUS INFECTION AMONG BLOOD DONORS WITH REACTIVE SCREENING RESULTS AT THE NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION OVER A 5-YEAR PERIOD (2020–2024)

Thị Thanh Dung Nguyễn1, , Vân Chi Trần1, Ngọc Quế Trần1
1 Viện Huyết học – Truyền máu Trung ương

Main Article Content

Abstract

Background: Confirmatory testing accurately determines HBV infection status in blood donors with reactive screening results, enhancing transfusion safety and donor management. Standardizing procedures and post-donation counseling are essential to minimize transmission risk and protect donor rights.


Objective: To determine the true prevalence of HBV infection among blood donors with reactive HBsAg and/or HBV-DNA screening results at the National Institute of Hematology and Blood Transfusion (2020–2024).


Method: A cross-sectional study.


Subjects: 1,922 blood donors with reactive HBV screening results (1,489 HBsAg-reactive, 433 HBV-DNA-reactive) who returned for confirmatory testing after 6 months.


Results: From 2020–2024, among 6,765 donors with reactive HBV screening, 1,922 (28.4%) returned for confirmation. 1,017 (53.0%) were confirmed HBV-infected, including 855 (44.5%) HBsAg-positive and 164 (8.5%) with occult hepatitis B infection (OBI). 697 (36.3%) were HBV-negative, and 206 (10.7%) had indeterminate results requiring follow-up.


Conclusion: Confirmatory testing is crucial to differentiate true infection from false-reactive results, ensuring transfusion safety and supporting appropriate donor counseling and management.

Keywords

HBV, blood donors, confirmatory testing, HBsAg, HBV-DNA

Article Details

References

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