REVIEW ABOUT THE ASSOCIATION BETWEEN GENES AND METABOLIC DISEASES BASED ON CircleDNA TEST

Trương Hồng Sơn1,, Nguyễn Xuân Ninh1, Lưu Liên Hương1, Lê Minh Khánh1
1 Vietnam Institute of Applied Medicine

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Abstract

Genes and metabolic syndromes is a branch of genomic testing, to determine the role of specific gene variants with metabolism-related characteristics, including the responses to diet, and the interactions between genes and diet on health status and the risk of metabolic diseases. Studies about genes and metabolism have shown that: 1) Genes that have been shown to be strongly associated with type 2 diabetes is TCF7L2, type 1 diabetes is SLC30A8, (2) The genes have been shown to be associated with all markers of dyslipidemia, including total cholesterol, LDL, HDL, and cholesterol, triglycerides are PCSK9 and LDLR, (3) Some polymorphisms of the FTO gene can increase the risk of overweight and obesity in many subjects such as adults, children... BDNF gene affects the regulation of homeostasis. energy, as well as cravings and related neurological disturbances, (4) Genes that have been shown to be associated with common cancers include MSH2 gene for colorectal cancer, BRCA1, BRCA2 for breast cancer

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References

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