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SIDE EFFECTS OF ADJUVANT CHEMOTHERAPY USING XELOX REGIMEN FOR COLON CANCER STAGE II,III AT DA NANG HOSPITAL
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Abstract
Objectives: Describe some clinical and subclinical characteristics of patients with stage II, III colon cancer at Da Nang hospital and evaluate the slide effects of adjuvant chemotherapy with XELOX regimen in the study group of patients. Subjects and methods: Descriptive clinical study with longitudinal follow-up on 66 patients diagnosed with high-risk stage II and stage III colon cancer treated at Danang Hospital from June 2017 to June 2020 Results: The mean age of the patients was 59.98 ± 10.33, the age group from 50-59 and 60-69 had the highest rate at 34.8%. The most common tumor site was the hepatic flexure colon 22.7%, the sigmoid colon 37.9%, moderate differentiation had the rate of 74.2%. Most of the treatment toxicity is in grade 1-2, rate of toxicity grade 3-4 on hematology, Hepatotoxicity, hand foot syndrome, peripheral neurotoxicity has the rate of 3%-4.5%. Conclusions: XELOX regimen is safe in adjuvant therapy in the study group of patients with mild side effects.
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Keywords
Colon cancer, XELOX
References
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