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Date Published: 25/02/2022
Abstract Views: 149
Views PDF: 114
DOI: https://doi.org/10.51298/vmj.v510i1.1938
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Vol. 510 No. 1 (2022)
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Các bài báo
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Thanh Tuân, P. . (2022). RESULT SURGERY OF MEDULLOBLASTOMA IN VIET DUC HOSPITAL. Vietnam Medical Journal, 510(1). https://doi.org/10.51298/vmj.v510i1.1938

RESULT SURGERY OF MEDULLOBLASTOMA IN VIET DUC HOSPITAL

Phạm Thanh Tuân1,
1 Hanoi Medical University

Main Article Content

Abstract

Total 53 patients medulloblastoma surgery in Viet Duc hospital with histopathological results, from 9/2016 to 9/2019. Age from 02 - 43, mean age 13.66±11.52. Male/Female ratio = 1.52/1. Headache occurred in 83%. MRi, 17% in the cerebellar hemisphere, 83% in cerebella vermis. Tumor size 30 - 50 mm was 81.13%. The mean preoperative Karnofsky score was 85.68±12.21. Soft density tumors  81.14%, rich in vessels 83%. Gross Total Rececion (GTR) 73.6%, Near Total Resection (NTR) 24.52%.  blood transfusion Intraoperative ranges from 250ml to 1050ml. There were no complications after surgery 69.86%, other complications were  3-9%. GOS score after surgery at grade 1 and 2 accounted was 83%, grade 3 accounted was 9.46%, grade 4 accounted was 7.54%. Medulloblastoma is a grade 4 brain tumor according to WHO. Tumor size > 30mm, almost in cerebella vermis. GOS results after surgery at grade 1,2 accounted was 83%, grade 3 was 9.46% and grade 4 was 7.54%.

Article Details

Keywords

Medulloblastoma, Karnofsky, GOS, complications

References

1. Tuyển BQ. Bệnh học thần kinh, sau đại học. Bệnh học thần kinh, sau đại học Nhà xuất bản quân đội nhân dân. 2003:207-224.
2. Millard NE, De Braganca KC. Medulloblastoma. Journal of Child Neurology. 2016;31(12):1341-1353.
3. Bavle A, Parsons DW. From One to Many: Further Refinement of Medulloblastoma Subtypes Offers Promise for Personalized Therapy. Cancer Cell. Jun 12 2017;31(6):727-729.
4. Poussaint TY, Rodriguez D. Advanced neuroimaging of pediatric brain tumors: MR diffusion, MR perfusion, and MR spectroscopy. Neuroimaging Clin N Am. Feb 2006;16(1):169-92, ix. doi:10.1016/j.nic.2005.11.005
5. JL H. Adult cerebellar medulloblastomas: the pathological, radiographic, and clinical disease spectrum. JNeurosurg. 1989;Vol 70:536-544.
6. Atalar B, Ozsahin M, Call J, et al. Treatment outcome and prognostic factors for adult patients with medulloblastoma: The Rare Cancer Network (RCN) experience. Radiother Oncol. Apr 2018;127(1):96-102. doi:10.1016/j.radonc.2017.12.028
7. Haque W, Verma V, Brian Butler E, Teh BS. Prognostic role of chemotherapy, radiotherapy dose, and extent of surgical resection in adult medulloblastoma. Journal of Clinical Neuroscience. 2020;76:154-160. doi:10.1016/j.jocn.2020.04.002
8. Lee ST, Lui TN, Chang CN, Cheng WC. Early postoperative seizures after posterior fossa surgery. J Neurosurg. Oct 1990;73(4):541-4. doi:10.3171 / jns.1990.73.4.0541
9. Rath GP, Bithal PK, Chaturvedi A, Dash HH. Complications related to positioning in posterior fossa craniectomy. J Clin Neurosci. Jun 2007;14(6):520-5. doi:10.1016/j.jocn.2006.02.010