RELATIONSHIP BETWEEN BONE DENSITIES AND SOME CLINICAL AND SUBCLINICAL FEATURES IN PATIENTS WITH LUPUS NEPHRITIS
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Abstract
Objectives: Investigate the relationship between bone density and some clinical and subclinical characteristics in patients with systemic lupus erythematosus who have been receiving long-term corticosteroid therapy. Subjects and methods: Cross-sectional study of 83 patients diagnosed with lupus nephritis. All patients were measured bone density by DEXA method. Results: The mean age of patients with lupus nephritis was 28.13 ± 9.21, the rate of male was 13.3%, female accounted for 86.7%. The mean duration of steroid treatment was 39.44 ± 43.74 months. Bone density was significantly related with duration of steroid use and BMI. Bone density is negatively correlated, moderately with BMI and with the duration of use steroid, the correlation coefficient is -0.454, p<0.001. Bone density is not related to age, renal failure status in patients with lupus nephritis who use high-dose and long-term steroids. Conclusion: Decreased bone density associated with overweight and obesity, long-term steroid use in patients with lupus nephritis.
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Keywords
Lupus nephritis, bone Density, duration of use steroid, BMI
References
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